DC Field | Value | Language |
dc.contributor | 國立臺灣大學應用力學研究所 | zh_TW |
dc.contributor.author | 邵耀華 | zh_TW |
dc.creator | 邵耀華 | - |
dc.date | 2001-07-31 | - |
dc.date.accessioned | 2006-08-23T05:03:16Z | - |
dc.date.accessioned | 2018-06-29T00:24:05Z | - |
dc.date.available | 2006-08-23T05:03:16Z | - |
dc.date.available | 2018-06-29T00:24:05Z | - |
dc.date.issued | 2001-07-31 | - |
dc.identifier | 892314B002505M08 | zh_TW |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/29688 | - |
dc.description.abstract | 本研究建立一非侵入式血管材質特性
量測系統,利用高頻率超音波同步記錄血
管的變形與相同位置血壓的脈動,以建立
血管壁應力與應變的變化歷程,進而對於
動脈血管的組織(血管硬度、順應性、黏彈
特性)提供一種簡便的非破壞性檢測。
實驗對象分為年輕、非糖尿病之老年
控制組及糖尿病三組,量測平躺及坐立時
之血管性質,觀察姿態改變後血管的因應
性及自主神經之控制能力。由結果發現隨
著年齡增加,足背動脈的應變減小(8.91
±0.88% vs. 6.96±1.95%, p<0.01),楊氏
係數增大( 0.90±0.11 ×106dyne/cm2 vs.
1.51±0.39 ×106dyne/cm2, p<0.01),EDR 增
加(5.60±1.29% vs. 8.08±1.61%)。年輕
組受姿態改變的變化較明顯。年齡增加可
能造成下肢動脈之交感神經變差。
糖尿病組之血壓普遍較控制組高,在
上肢血管的應變量減小,楊氏係數增加。
足背動脈的應變量變小(6.96±1.95% vs.
6.36±2.05%),楊氏係數增加(1.51±0.39 vs.
1.61±0.43 ×106dyne/cm2),EDR 明顯增加
(8.08±1.61% vs. 11.51±2.07%)。顯示下
肢動脈受糖尿病的影響較大。糖尿病組姿
態改變後,下肢管徑的變化量不明顯,表
示其腿部交感神經束的作用已經變差。。 | zh_TW |
dc.description.abstract | A novel methodology was developed
for the detection of arterial mechanical
properties non-invasively using
high-resolution ultrasound. The vascular
wall motion is recorded simultaneously
with the pulsatile pressure, thus the
stress-strain relationship can be derived
accurately.
The subjects studied were divided into
three groups: young, diabetic patients and
their age-matched control. Postural change
was adopted to investigate the vascular
muscle tone and sympathetic response of
peripheral arteries. Results show that the
vessel distensibility at the dsalis pedis artery
(DPA) decrease substantially with age
(8.91±0.88% vs. 6.96±1.95%, p<0.01), the
corresponding arterial elastic modulus
increase (0.90±0.11vs.1.51±0.39 Mdyne/cm2,
p<0.01) and the energy dissipation ratio
(EDR) increase (5.60±1.29% vs.
8.08±1.61%). The arterial mechanical
properties of young group reacted more
effectively to the postural variation, which
suggested that the autonomic function in the
lower extremity would decay with age.
The diabetic patients have higher mean
arterial pressure than the control group, their
peripheral arterial distensibility decrease, the
pressure-diameter elastic modulus increase
and EDR increase notably (DPA: 8.08±
1.61% vs.11.51±2.07%). The peripheral
arteries in the lower extremity of DM patient
were significantly affected by the circulatory
diseases than the vessels in the upper trunk,
this signifies the lost or degeneration of
sympathetic tone in diabetic foot. | en |
dc.format | application/pdf | zh_TW |
dc.format.extent | 73068 bytes | - |
dc.format.mimetype | application/pdf | - |
dc.language | zh-TW | zh_TW |
dc.language.iso | zh_TW | - |
dc.publisher | 臺北市:國立臺灣大學應用力學研究所 | zh_TW |
dc.rights | 國立臺灣大學應用力學研究所 | zh_TW |
dc.subject | 超音波 | zh_TW |
dc.subject | 動脈黏彈特性 | zh_TW |
dc.subject | 糖尿病 | zh_TW |
dc.subject | Ultrasound | en |
dc.subject | Peripheral Arteria | en |
dc.subject | Viscoelasticity | en |
dc.subject | Diabetic Mellitus | en |
dc.subject.classification | [SDGs]SDG3 | - |
dc.title | 非侵入式週邊動脈血管機械特性量測技術研發(II) | zh_TW |
dc.title | Non-invasive measurement of mechanical properties of peripheral arteries | en |
dc.type | report | en |
dc.identifier.uri.fulltext | http://ntur.lib.ntu.edu.tw/bitstream/246246/29688/1/892314B002505M08.pdf | - |
dc.coverage | 計畫年度:89
第二期;起迄日期:2000-08-01/2001-07-31 | zh_TW |
item.openairecristype | http://purl.org/coar/resource_type/c_93fc | - |
item.openairetype | report | - |
item.languageiso639-1 | zh_TW | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.fulltext | with fulltext | - |
Appears in Collections: | 應用力學研究所
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