https://scholars.lib.ntu.edu.tw/handle/123456789/86187
Title: | 行政院國家科學委員會專題研究計畫成果報告:砷暴露對魚之毒性和生化效應之比較探討以及生物指標之建立 | Authors: | 廖秀娟 | Keywords: | 砷;毒性效應;生化效應;生物指標;arsenic;comparative toxicity;biochemical effects;biomarker | Issue Date: | 2004 | Publisher: | 臺北市:國立臺灣大學生物環境系統工程學系暨研究所 | Abstract: | 水污染對人類健康及環境造成潛在的風險。當生物體暴露於特定的金屬污染物時,會 造成多種不同的毒性效應,例如:立即性的死亡,或緩慢的引發癌症效應。本研究計畫之 主要目標,將探討不同物種(III, V)砷暴露,對魚之毒性及其生化效應之關係。另外,對砷 在不同的魚組織的濃度分布,以及其生化效應亦加以探討。另外,本計畫將建立砷暴露之 生物指標。本研究計畫之結果,將有助於了解砷物種之毒性效應,以及其相關的生化反應, 並藉由生物指標之建立,用來偵測水中砷污染。 Water contaminants cause a high potential risk to human health and the environment. Exposure of humans and animals to certain metal derivatives results in a variety of toxic effects ranging from immediate mortality to slow process of carcinogenesis. The primary goal of this proposal is to investigate the comparative toxicity of arsenic compounds and the corresponding biochemical effects in aquatic organisms as well as developing mechanism-based biomarkers. The toxicological responses of different redox speciation of arsenic in aquatic system will be investigated. Moreover, the biochemical effects of arsenic at different target sites of fish tilapia will be examined. Furthermore, biomarker of arsenic exposure and effect will be developed. The studies employed in this proposal will reflect the specific toxic effect of arsenic and reveal fundamental relationships between chemical structures and biological activity. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/10774 | Other Identifiers: | 922313B002108 | Rights: | 國立臺灣大學生物環境系統工程學系暨研究所 |
Appears in Collections: | 生物環境系統工程學系 |
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922313B002108.pdf | 97.42 kB | Adobe PDF | View/Open |
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