dc.relation.reference | 王斯郁。2002。Clodronate及Paclitaxel對人類肝癌細胞株之作用評估。陽明大學藥理學研究所。碩士論文。
林雅姿。2002。中藥配醣體之體循環前代謝。中國醫藥學院藥物化學研究所。博士論文。
林苡芬。2004。不同發酵碳源之牛樟芝菌絲體發酵濾液對人類肝癌細胞株之影響。台灣大學食品科技研究所。碩士論文。
吳志忠。2002。大蒜精油及其含硫化合物在不同實驗模式中調控抗氧化及生物轉換作用之能力與對人類J-5肝癌細胞株及其細胞週期之影響。中興大學食品科學研究所。博士論文。
邱哲琳。2002。核苷誘導人類肝癌細胞株HepG2與Hep3B細胞程式凋亡之影響。台北醫學大學保健營養所。碩士論文。
陳嘉琳。2004。薑精油對肝癌細胞及正常肝細胞生理機能之影響。台灣大學食品科技研究所。碩士論文。曾岐原。1999。最新病理學。第二版。匯華圖書出版有限公司。pp 377-339。
鍾淳雁。2004。以TGF-β1處理之Hep 3B與HSC-T6模式探討「靈芝-豆科」發酵液之抑制肝纖維化效果。台灣大學食品科技研究所。碩士論文。
Anundi I, Hogberg J, Stead AH. 1979. Glutathione depletion in isolated hepatocytes: its relation to lipid peroxidation and cell damage. Acta Pharmacol Toxicol 45(1): 45-51.
Aoi W, Niisato N, Miyazaki H, Marunaka Y. 2004. Flavonoid-induced reduction of ENaC expression in the kidney of Dahl salt-sensitive hypertensive rat. Biochem Biophys Res Commun 315(4): 892-896.
Bast A, Haenen GR, Doelman CJ. 1991. Oxidants and antioxidants: state of the art. Am J Med 91(3C):2S-13S.
Beasley RP, Hwang LY, Lin CC, Chien CS. 1981. Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22 707 men in Taiwan. Lancet 2(8256):1129-1133.
Bellomo G, Mirabelli F, DiMonte D, Richelmi P, Thor H, Orrenius C, Orrenius S. 1987. Formation and reduction of glutathione-protein mixed disulfides during oxidative stress. A study with isolated hepatocytes and menadione (2-methyl-1,4-naphthoquinone). Biochem Pharmacol 36(8): 1313-1320.
Berry MN, Friend DS. 1973. High yield production of isolated rat liver parenchymal cells: a biochemical and fine structural study. J Biol Chem 59: 722-734.
Block G, Patterson B, Subar A. 1992. Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 18: 1-29.
Bonney RJ, Becker JE, Walker PR, Potter VR. 1973. Primary monolayer cultures of adult rat liver parenchymal cells suitable for study of the regulation of enzyme synthesis. In Vitro 9(6): 399-413.
Bressac B, Galvin KM, Liang TJ, Isselbacher KJ, Wands JR, Ozturk M. 1990. Abnormal structure and expression of p53 gene in human hepatocellular carcinoma. Proc Natl Acad Sci USA 87(5): 1973-1977.
Brody TM., Larner J, Minneman KP. 1998. Human pharmacology: molecular to clinical. Mosby, St. Louis, USA. pp 30-50.
Bruix J, Sherman M, Llovet JM, Beaugrand M, Lencioni R, Burroughs AK, Christensen E, Pagliaro L, Colombo M, Rodes J; EASL Panel of Experts on HCC. 2001. Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver. J Hepatol 35(3):421-430.
Budavari S. The Merck Index, Merck & Co. Inc., 13th ed., NJ, USA. 2001; pp. 1438-1439.
Buja LM, Eigenbrodt ML, Eigenbrodt EH. 1993. Apoptosis and necrosis. Basic types and mechanisms of cell death. Arch Pathol Lab Med 117(12): 1208-1214.
Chisari FV, Klopchin K, Moriyama T, Pasquinelli C, Dunsford HA, Sell S, Pinkert CA, Brinster RL, Palmiter RD. 1989. Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell 59(6):1145-1156.
de Whalley CV, Rankin SM, Hoult JR, Jessup W, Leake DS. 1990 Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages. Biochem Pharmacol 39(11): 1743-1750.
Derradji H, Baatout S. 2003. Apoptosis: a mechanism of cell suicide. In Vivo 17(2): 185-192.
Di Bisceglie AM. 1997. Hepatitis C and hepatocellular carcinoma. Hepatology 26(3 Suppl 1): 34S-38S.
Duarte J, Perez-Palencia R, Vargas F, Ocete MA, Perez-Vizcaino F, Zarzuelo A, Tamargo J. 2001. Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats. Br J Pharmacol 133(1): 117-124.
Elangovan V, Sekar N, Govindasamy S. 1994. Chemopreventive potential of dietary bioflavonoids against 20-methylcholanthrene-induced tumorigenesis. Cancer Lett 87(1): 107-113.
Evans P, Halliwell B. 1999. Free radicals and hearing. Cause, consequence, and criteria. Ann NY Acad Sci 884: 19-40.
Ewald C, Fjelkner-Modig S, Johansson K, Sjöholm I, Åkesson B. 1999. Effect of processing on major flavonoids in processed onions, green beans, and peas. Food Chem 64: 231-235.
Filipe P, Morliere P, Patterson LK, Hug GL, Maziere JC, Maziere C, Freitas JP, Fernandes A, Santus R.. 2002. Mechanisms of flavonoid repair reactions with amino acid radicals in models of biological systems: a pulse radiolysis study in micelles and human serum albumin. Biochim Biophys Acta 1572(1): 150-162.
Fischer SM, Mills GD, Slaga TJ. 1982. Inhibition of mouse skin tumor promotion by several inhibitors of arachidonic acid metabolism. Carcinogenesis 3(11): 1243-1245.
Fraga CG, Leibovitz BE, Tappel AL. 1988. Lipid peroxidation measured as thiobarbituric acid-reactive substances in tissue slices: characterization and comparison with homogenates and microsomes. Free Radic Biol Med 4(3): 155-161.
Frankel EN, Kanner J, German JB, Parks E, Kinsella JE. 1993. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine. Lancet 341(8843): 454-457.
Gee JM, DuPont MS, Day AJ, Plumb GW, Williamson G, Johnson IT. 2000. Intestinal transport of quercetin glycosides in rats involves both deglycosylation and interaction with the hexose transport pathway. J Nutr 130(11): 2765-2771.
Gross A, McDonnell JM, Korsmeyer SJ. 1999. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 13(15):1899-1911.
Gugler R, Leschik M, Dengler HJ. 1975. Disposition of quercetin in man after single oral and intravenous doses. EurJ Clin Pharmacol 9: 229-234.
Habig WH, Pabst MJ, Jakoby WB. 1974. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 249(22): 7130-7139.
Haddad JJ. 2002. Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology. Respir Res 3(1): 26
Halliwell B, Murcia MA, Chirico S, Aruoma OI. 1995. Free radicals and antioxidants in food and in vivo: what they do and how they work. Crit Rev Food Sci Nutr 35(1-2): 7-20.
Halliwell B, Whiteman M. 2004. Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean. Br J Pharmacol 142(2): 231-255.
Hansen RK, Oesterreich S, Lemieux P, Sarge KD, Fuqua SA. 1997. Quercetin inhibits heat shock protein induction but not heat shock factor DNA-binding in human breast carcinoma cells. Biochem Biophys Res Commun 239(3): 851-856.
Hengartner MO. 2000. The biochemistry of apoptosis. Nature 407(6805): 770-776.
Hertog MG, Hollman PC. 1996. Potential health effects of the dietary flavonol quercetin. Eur J Clin Nutr 50(2): 3-71.
Hertog MG, Peter C. H. Hollman, and Martijn B. Katan. 1992. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands. J Agric Food Chem 40: 2379-2383.
Hollman PC, van Trijp JM, Buysman MN, van der Gaag MS, Mengelers MJ, de Vries JH, Katan MB. 1997. Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man. FEBS Lett 418(1-2): 152-156.
Hosokawa N, Hosokawa Y, Sakai T, Yoshida M, Marui N, Nishino H, Kawai K, Aoike A. 1990. Inhibitory effect of quercetin on the synthesis of a possibly cell-cycle-related 17-kDa protein, in human colon cancer cells. Int J Cancer 45(6): 1119-1124.
Huang MT, Wood AW, Newmark HL, Sayer JM, Yagi H, Jerina DM, Conney AH. 1983. Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by phenolic plant flavonoids. Carcinogenesis 4(12): 1631-1637.
Husain SR, Cillard J, Cillard P. 1987. Hydroxy radical scavenging activity of flavonoids. Phytochemistry 26: 2489-2492.
Ioku K, Tsushida T, Takei Y, Nakatani N, Terao J. 1995. Antioxidative activity of quercetin and quercetin monoglucosides in solution and phospholipid bilayers. Biochim Biophys Acta 1234(1): 99-104.
Kerr JF, Wyllie AH, Currie AR. 1972. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26(4): 239-257.
Kerr JF, Winterford CM, Harmon BV. 1994. Apoptosis. Its significance in cancer and cancer therapy. Cancer 73(8): 2013-2026.
Kim SH, Jang YP, Sung SH, Kim CJ, Kim JW, Kim YC. 2003. Hepatoprotective dibenzylbutyrolactone lignans of Torreya nucifera against CCl4-induced toxicity in primary cultured rat hepatocytes. Biol Pharm Bull 26(8):1202-1205.
Kiso Y, Tohkin M, Hikino H. 1983. Assay method for antihepatotoxic activity using carbon tetrachloride induced cytotoxicity in primary cultured hepatocytes. Planta Med 49(4): 222-225.
Knekt P, Jarvinen R, Reunanen A, Maatela J. 1996. Flavonoid intake and coronary mortality in Finland: a cohort study. BMJ 312(7029): 478-481.
Kosower, N. S. and Kosower, E. M. 1978. The glutathione status of cells. Internatl Rev. Cytol 54: 109-160.
Kreamer BL, Staecker JL, Sawada N, Sattler GL, Hsia MT, Pitot HC. 1986. Use of a low-speed, iso-density percoll centrifugation method to increase the viability of isolated rat hepatocyte preparations. In Vitro Cell Dev Biol 22(4): 201-211.
Kuo SM. 1996. Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells. Cancer Lett 110(1-2): 41-48
Lamson DW, Brignall MS. 2000. Antioxidants and cancer, part 3: quercetin. Altern Med Rev 5(3): 196-208.
Lawrence RA, Burk RF. 1976. Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun 71(4): 952-958.
Lebrec D. 1994. Pharmacological treatment of portal hypertension: hemodynamic effects and prevention of bleeding. Pharmacol Ther 61(1-2):65-107.
Lee ES, Lee HE, Shin JY, Yoon S, Moon JO. 2003. The flavonoid quercetin inhibits dimethylnitrosamine-induced liver damage in rats. J Pharm Pharmacol 55(8): 1169-1174.
Le Marchand L. 2002. Cancer preventive effects of flavonoids--a review. Biomed Pharmacother 56(6): 296-301.
Lii CK, Hendrich S. 1993. Selenium deficiency suppresses the S-glutathiolation of carbonic anhydrase III in rat hepatocytes under oxidative stress. J Nutr 123(9): 1480-6.
Liu IM, Sheu SJ. 1989. Analysis and processing of Chinese herbal drugs. VIII: The study of sophorae floe. Am J Chin Med 17(3-4): 179-187.
Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193(1): 265-275.
Matsukawa Y, Nishino H, Okuyama Y, Matsui T, Matsumoto T, Matsumura S, Shimizu Y, Sowa Y, Sakai T. 1997. Effects of quercetin and/or restraint stress on formation of aberrant crypt foci induced by azoxymethane in rat colons. Oncology 54(2): 118-21.
Maxwell SR. 1992. Prospects for the use of antioxidant therapies. Drugs 49: 345-361.
Meister A. 1984. New aspects of glutathione biochemistry and transport-selective alteration of glutathione metabolism. Nutr Rev 42(12): 397-410.
Minamoto T, Mai M, Ronai Z. 1999. Environmental factors as regulators and effectors of multistep carcinogenesis. Carcinogenesis 20(4): 519-527.
Mizuno M, Tsuchida H, Kozukue N, Mizuno S. 1992. Rapid quantitative analysis and distribution of free quercetin in vegetables and fruits. Nippom Shokuhin Kogyo Gakkaishi 39: 88-92. (in Japanese)
Mookerjee BK, Lee TP, Lippes HA, Middleton E Jr. 1986. Some effects of flavonoids on lymphocyte proliferative responses. J Immunopharmacol 8(3): 371-392.
Morand C, Crespy V, Manach C, Besson C, Demigne C, Remesy C. 1998. Plasma metabolites of quercetin and their antioxidant properties. Am J Physiol 275(1 Pt 2): R212-R219.
Morel I, Lescoat G, Cogrel P, Sergent O, Pasdeloup N, Brissot P, Cillard P, Cillard J. 1993. Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures. Biochem Pharmacol 45(1): 13-19.
Morino K, Matsukara N, Kawachi T, Ohgaki H, Sugimura T, Hirono I. 1982. Carcinogenicity test of quercetin and rutin in golden hamsters by oral administration. Carcinogenesis 3(1): 93-97.
Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63.
Murota K, Terao J. 2003. Antioxidative flavonoid quercetin: implication of its intestinal absorption and metabolism. Arch Biochem Biophys 417(1): 12-17.
Negre-Salvayre A, Salvayre R. 1992. Quercetin prevents the cytotoxicity of oxidized LDL on lymphoid cell lines. Free Radic Biol Med 12(2): 101-106.
Ng TB, Liu F, Lu Y, Cheng CH, Wang Z. 2003. Antioxidant activity of compounds from the medicinal herb Aster tataricus. Comp Biochem Physiol C Toxicol Pharmacol 136(2): 109-115.
Nguyen TT, Tran E, Nguyen TH, Do PT, Huynh TH, Huynh H. 2004. The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells. Carcinogenesis 25(5): 647-659.
O'Leary KA, Day AJ, Needs PW, Mellon FA, O'Brien NM, Williamson G. 2003. Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism. Biochem Pharmacol 65(3): 479-491.
Oliveira EJ, Watson DG, Grant MH. 2002. Metabolism of quercetin and kaempferol by rat hepatocytes and the identification of flavonoid glycosides in human plasma. Xenobiotica 32(4): 279-287.
Oyama Y, Fuchs PA, Katayama N, Noda K. 1994. Myricetin and quercetin, the flavonoid constituents of Ginkgo biloba extract, greatly reduce oxidative metabolism in both resting and Ca(2+)-loaded brain neurons. Brain Res 635(1-2): 125-9.
Paganga G, Rice-Evans CA. 1997. The identification of flavonoids as glycosides in human plasma. FEBS Lett 401(1): 78-82.
Pavanato A, Tunon MJ, Sanchez-Campos S, Marroni CA, Llesuy S, Gonzalez-Gallego J, Marroni N. 2003. Effects of quercetin on liver damage in rats with carbon tetrachloride-induced cirrhosis. Dig Dis Sci 48(4): 824-829.
Perez-Vizcaino F, Ibarra M, Cogolludo AL, Duarte J, Zaragoza-Arnaez F, Moreno L, Lopez-Lopez G, Tamargo J. 2002. Endothelium-independent vasodilator effects of the flavonoid quercetin and its methylated metabolites in rat conductance and resistance arteries. J Pharmacol Exp Ther 302(1): 66-72.
Peterson J, Dwyer J. 1998. Flavonoids: dietary occurrence and biochemical activity. Nutr Res 18(12): 1995-2018.
Reed DJ, Babson JR, Beatty PW, Brodie AE, Ellis WW, Potter DW. 1980. High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides. Anal Biochem 106(1): 55-62.
Rice-Evans CA, Miller NJ, Paganga G. 1996. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med 20(7): 933-956.
Robak J, Gryglewski RJ. 1988. Flavonoids are scavengers of superoxide anions. Biochem Pharmacol 37(5): 837-841.
Sano M, Motchnik PA, Tappel AL. 1986. Halogenated hydrocarbon and hydroperoxide-induced peroxidation in rat tissue slices. Free Radic Biol Med 2(1): 41-48.
Saxena R, Zucker SD, Crawford JM. 2003. Anatomy and physiology of the liver. In: Zakim D, Boyer TD, eds. Hepatology: a textbook of liver disease, 4th ed. WB Saunders, Philadelphia, Pennsylvania, USA, 3-30.
Schafer KA. 1998. The cell cycle: a review. Vet Pathol 35(6): 461-478.
Shafritz DA, Kew MC. 1981. Identification of integrated hepatitis B virus DNA sequences in human hepatocellular carcinomas. Hepatology 1(1): 1-8.
Siess MH, Leclerc J, Canivenc-Lavier MC, Rat P, Suschetet M. 1995. Heterogenous effects of natural flavonoids on monooxygenase activities in human and rat liver microsomes. Toxicol Appl Pharmacol 130(1): 73-78.
Smith ML, Fornace AJ Jr. 1996. Mammalian DNA damage-inducible genes associated with growth arrest and apoptosis. Mutation Research 340 (2-3): 109-124.
Surh Y. 1999. Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutat Res 428(1-2): 305-27.
Terao J, Piskula M, Yao Q. 1994. Protective effect of epicatechin, epicatechin gallate, and quercetin on lipid peroxidation in phospholipid bilayers. Arch Biochem Biophys 308(1): 278-284.
Vermeulen K, Van Bockstaele DR, Berneman ZN. 2003. The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer. Cell Prolif 36(3): 131-149
Wattenberg LW. 1985. Chemoprevention of cancer. Cancer Res 45(1): 1-8.
Wiseman H, Halliwell B. 1996. Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem J 313 ( Pt 1): 17-29.
Yeh FS, Yu MC, Mo CC, Luo S, Tong MJ, Henderson BE. 1989. Hepatitis B virus, aflatoxins, and hepatocellular carcinoma in southern Guangxi, China. Cancer Res 49(9): 2506-2509
Yoshida M, Sakai T, Hosokawa N, Marui N, Matsumoto K, Fujioka A, Nishino H, Aoike A. 1990. The effect of quercetin on cell cycle progression and growth of human gastric cancer cells. FEBS Lett 260(1): 10-3.
Yoshida M, Yamamoto M, Nikaido T. 1992. Quercetin arrests human leukemic T-cells in late G1 phase of the cell cycle. Cancer Res 52(23): 6676-6681. | zh_TW |