As cells are the fundamentals of life, it is important to understand the molecular interactions and functions inside a cell. Given that, faculty members of our institute have been investigating the genomics, gene-regulated cellular structures and functions, mechanisms of development and inheritance for a variety of model organisms. All the studies are not possible without the tools and knowledge from molecular biology, cell biology, genetics, developmental biology, systems biology, and synthetic biology. The model organisms we have used include, but not limited to, E. coli, yeasts, C. elegans, flies, zebrafish, Arabidopsis, and rats; they are classified from prokaryotes to eukaryotes, from unicellular to multicellular species, and from worms to mammals. With the diverse organisms and research tools, we can systematically explore the miracle of life at the molecular and cellular levels, as well as from different points of view. We can further compare and contrast the results obtained from different organisms. However, any research should not be confined by the existing tools and methods. Interdisciplinary research is prevailing nowadays, along with emergence of novel ideas and advanced technologies. Our faculty would take advantage of the state-of-the-art approaches, such as nanomaterials and super-resolution imaging, to make a breakthrough and excel in research, either by setting up the desired systems or by collaborating with other groups. We wish any new faculty members to join us in the future will also bring innovative concepts and research. In conclusion, with the study of various model organisms and the employment of novel technologies, our goal is to train students to have contemporary and advanced biological skills, such that they can contribute to the development of biotechnology, medicine, and agriculture of our nation, and thus our research of life science can be promoted and competitive internationally.