Wang, Li-TzuLi-TzuWangYen, B LinjuB LinjuYenWang, Hsiu-HuanHsiu-HuanWangChao, Ying-YinYing-YinChaoLee, WeiWeiLeeHuang, Li-YuehLi-YuehHuangChiu, Sheng-KangSheng-KangChiuSiu, L KristopherL KristopherSiuLiu, Ko-JiunnKo-JiunnLiuSytwu, Huey-KangHuey-KangSytwuMEN-LUH YEN2022-06-172022-06-1720230040-6376https://scholars.lib.ntu.edu.tw/handle/123456789/613027Acute respiratory distress syndrome (ARDS) is a lethal complication of severe bacterial pneumonia due to the inability to dampen overexuberant immune responses without compromising pathogen clearance. Both of these processes involve tissue-resident and bone marrow (BM)-recruited macrophage (MΦ) populations which can be polarised to have divergent functions. Surprisingly, despite the known immunomodulatory properties of mesenchymal stem cells (MSCs), simultaneous interactions with tissue-resident and recruited BMMΦ populations are largely unexplored.enARDS; bacterial Infection; macrophage biology; respiratory infection[SDGs]SDG3Placental mesenchymal stem cells boost M2 alveolar over M1 bone marrow macrophages via IL-1β in Klebsiella-mediated acute respiratory distress syndromejournal article10.1136/thoraxjnl-2021-217928354509432-s2.0-85130779148WOS:000786580900001https://scholars.lib.ntu.edu.tw/handle/123456789/612859