El-Gamal, Ali A. H.Ali A. H.El-GamalWang, Shang-KweiShang-KweiWangCHANG-FENG DAIChen, I-GinI-GinChenDuh, Chang-YihChang-YihDuh2009-12-172018-06-282009-12-172018-06-282005http://www.scopus.com/inward/record.url?eid=2-s2.0-12944333064&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/315000http://ntur.lib.ntu.edu.tw/bitstream/246246/174404/1/47.pdfTen new prenylbicyclogermacrane diterpenoids, pacificins A-J (1-10), were isolated from the methylene chloride solubles of the Formosan soft coral Nephthea pacifica. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.application/pdf85802 bytesapplication/pdfen-US[SDGs]SDG3[SDGs]SDG14dichloromethane; diterpenoid; pacificin A; pacificin B; pacificin C; pacificin D; pacificin E; pacificin F; pacificin G; pacificin H; pacificin I; pacificin J; unclassified drug; animal cell; article; cancer cell; carbon nuclear magnetic resonance; controlled study; coral; cytotoxicity; drug isolation; drug structure; human; human cell; in vitro study; nonhuman; nuclear Overhauser effect; proton nuclear magnetic resonance; Animals; Anthozoa; Antineoplastic Agents; Diterpenes; Drug Screening Assays, Antitumor; Leukemia P388; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Taiwan; Alcyonacea; Animalia; Anthozoajournal article10.1021/np040160e2-s2.0-12944333064WOS:000227029000015http://ntur.lib.ntu.edu.tw/bitstream/246246/174404/1/47.pdf