Lin, Yu-LiYu-LiLinCheng, Pei-YunPei-YunChengChin, Chiao-LiChiao-LiChinChuang, Kuan-TingKuan-TingChuangJING-YI LINChang, NingNingChangPan, Chun-KeiChun-KeiPanLin, Cheng-ShengCheng-ShengLinPan, Siao-CianSiao-CianPanBOR-LUEN CHIANG2024-01-152024-01-152023-12-181423-0127https://scholars.lib.ntu.edu.tw/handle/123456789/638483Human enteroviruses A71 (EV-A71) and D68 (EV-D68) are the suspected causative agents of hand-foot-and-mouth disease, aseptic meningitis, encephalitis, acute flaccid myelitis, and acute flaccid paralysis in children. Until now, no cure nor mucosal vaccine existed for EV-A71 and EV-D68. Novel mucosal bivalent vaccines are highly important for preventing EV-A71 and EV-D68 infections.enAcute flaccid myelitis; Acute flaccid paralysis; Adjuvant; Enterovirus A71; Enterovirus D68; Ganoderma lucidum polysaccharide; Intranasal; Mucosal vaccine[SDGs]SDG3A novel mucosal bivalent vaccine of EV-A71/EV-D68 adjuvanted with polysaccharides from Ganoderma lucidum protects mice against EV-A71 and EV-D68 lethal challengejournal article10.1186/s12929-023-00987-3381109402-s2.0-85180238977https://api.elsevier.com/content/abstract/scopus_id/85180238977