CHIN-HSIAO TSENG2020-06-012020-06-0119991023-2141https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032707875&partnerID=40&md5=2d37e31dae03dcafbc6beba78155d7d9https://scholars.lib.ntu.edu.tw/handle/123456789/496232Diabetes mellitus is the fifth leading cause of death in Taiwan. More than 75% of causes of death in diabetic patients can be ascribed to atherosclerosis. Cigarette smoking has long been identified as an independent risk factor of cardiovascular disease. In the USA, about 30% of cardiovascular mortality each year can be ascribed to cigarette smoking, and about 65% of cardiovascular mortality in diabetic patients can be ascribed to an interaction between diabetes mellitus and cigarette smoking. The incidence, recurrence rate, and mortality of cardiovascular disease in diabetic patients are all higher in smokers than in non-smokers. Smoking cessation can improve these phenomena. Patients after myocardial infarction experienced a 50% reduction in cardiovascular events after quitting smoking for 1 year. The risk was further reduced after quitting for 2 two years to a level comparable to patients who did not smoke. Analysis of the theoretical benefits of four different approaches to reducing cardiovascular risk in diabetic and non-diabetic populations in the Multiple Risk Factor Intervention Trial (MRFIT) concluded that smoking cessation is the most effective intervention when compared to antihypertensive treatment, aspirin, and cholesterol lowering. Diabetic patients are prone to gain more beneficial effects than are non-diabetics from preventive interventions.Cardiovascular disease; Cigarette smoking; Diabetes mellitus; Preventive medicine; Smoking cessation[SDGs]SDG3acetylsalicylic acid; cholesterol; hypocholesterolemic agent; antihypertensive therapy; article; atherosclerosis; cardiovascular disease; cause of death; cigarette smoking; diabetes mellitus; heart infarction; human; mortality; recurrence risk; risk factor; smoking cessation; Taiwan; United Statesjournal article2-s2.0-0032707875