Ting, MaoMaoTingCHIH-HSIEN WANGNAI-HSIN CHIRON-BIN HSUYIH-SHARNG CHENHSI-YU YU2021-05-072021-05-0720200929-6646https://www.scopus.com/inward/record.uri?eid=2-s2.0-85062709166&doi=10.1016%2fj.jfma.2019.02.009&partnerID=40&md5=9f79e2b49e505709fad099493ce9df36https://scholars.lib.ntu.edu.tw/handle/123456789/560279Background: Surgical treatment of infective endocarditis (IE) with aortic periannular abscess (PA) is a challenging issue with high mortality and morbidity rate in the current era. The present study is to review the results of surgical treatment for IE-PA based on an anatomy-guided surgical procedure selection for either aortic valve replacement (AVR) or aortic root reconstruction (ARR). Methods: Patients with IE-PA received surgical treatment in National Taiwan University Hospital during the years 2001-2017 were retrospectively reviewed. The selection of surgical procedure was based on the intraoperative anatomical finding. The AVR group consisted of isolated AVR or AVR with patch repair if PA involved less than one cusp of the annulus. The ARR group included aortic root replacement if PA involved more than one cusp, causing commissural/sub-commissural destruction. In-hospital mortality and mid-term outcome and the risk factors were examined. Results: In-hospital mortality was 13% in the AVR group (24 patients) and 25% in the ARR group (8 patients) (p = 0.578). The composite adverse events (cardiac death, valve reoperation, or paravalvular leak) rate was 31% in the AVR group and 40% in the ARR group at one year; 48% in the AVR group and 40% in the ARR group at five years; 55% in the AVR group and 40% in the ARR group at ten years. Conclusion: Anatomy-guided surgical procedure selection for IE-PA is feasible. With the appropriate selection, ARR may be associated with fewer adverse events in mid-term follow-up. Careful intraoperative judgment and management and long-term follow-up are warranted for these patients.enAortic root reconstructionAortic valve replacementBentall's procedureInfective endocarditisPeriannular abscessjournal article10.1016/j.jfma.2019.02.009308797172-s2.0-85062709166