2010-08-012024-05-13https://scholars.lib.ntu.edu.tw/handle/123456789/646094摘要：過去的文獻顯示早期介入有助於增進早產兒的短期發展表現，並降低其父母親的壓力，尤其對於出生體重較重之早產兒有較佳之介入效果。然而，較少研究探討早期介入對於週數或體重較小的早產兒的療效，並針對多面向預後進行長期的追蹤評估。本研究團隊近年進行了一個臨床隨機試驗，探討三種不同的介入方式：常規性照護、以門診為基礎的早期介入、與以居家為基礎的早期介入，對於極低出生體重早產兒(出生體重低於1,500公克)，於出生後至矯正年齡兩歲期間之療效。後兩者的介入為全面且密集性的介入計畫，從早產兒住院期開始至矯正年齡一歲為止，給予嬰兒以及其家長方面的介入，而介入的地點則分別在診間與早產兒家中。本次所提之三年期計畫將延續過去的研究，持續追蹤180名極低出生體重早產兒於3及4歲的長期預後，以幫助了解早期介入之持續性療效。本計畫亦將包括60名足月兒，以做為早產兒發展表現之對照。預後的評估將包含兒童表現〔健康、生長、神經發展與行為〕、親職功能〔父母親壓力、勝任感、親職效能以及家庭支持〕與親子互動〔玩樂與挫敗情境〕。本研究之早期介入療效的長期追蹤結果，將可提供相關早療人員與醫療政策決策者，做為未來對於發展障礙高危險性早產兒擬定早期介入計畫之參考。<br> Abstract: Accumulating data on early intervention for preterm infants illustrated short-term benefits on enhancing child development and decreasing parental stress, particularly for those of heavier birth weights. However, rare studies had designed early intervention program for small preterm infants and longitudinally examined the effectiveness in various outcome domains. Our research team recently conducted a clinical randomization trial on the effectiveness of three early intervention programs: usual care program (UCP), clinic-based intervention program (CBIP) and home-based intervention program (HBIP) on very low birth weight (VLBW, birth weight <1,500 g) preterm infants from the neonatal period to two years corrected age (CA). The latter two were comprehensive, intensive intervention programs that combined child- and parent-focused services beginning in hospitalization and ending at one year CA as delivered at clinic and home respectively. This three-year research project has extended our previous work to longitudinally examine the effectiveness of the three intervention programs in 180 VLBW preterm infants at 3 and 4 years of age. Sixty full-term infants will also be included to serve as the reference group. Outcome measures will include child (i.e., health, growth, neurodevelopment and behavior), parenting (i.e., parental stress, competency, efficacy and family support) and mother-child transactions (i.e., free-play and frustrating episode). The longitudinal data on the effectiveness of these early intervention programs for VLBW preterm infants will provide important information to help early intervention professionals and public policy makers to develop effective intervention for preterm children at risk for developmental problems.期介入親子互動神經發展預後親職早產學齡前Early interventionMother-Child InteractionNeurodevelopmentParentingPrematurityPreschool Age