Chang C.-WChen S.HJENG-YUH KOLin Y.-H.2021-11-182021-11-1820080179-051Xhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-44549084094&doi=10.1007%2fs00455-007-9128-x&partnerID=40&md5=d5d068f4607478df71a3ad40a180c507https://scholars.lib.ntu.edu.tw/handle/123456789/587165The purpose of this study was to investigate early radiation effects on tongue function for patients with nasopharyngeal carcinoma (NPC) and to provide a scientific database for early intervention plans. Twelve subjects with NPC and 12 age- and sex-matched normal subjects were included. Tongue maximum isometric strength and endurance at 50% of maximum strength were obtained once from normal subjects with the Iowa Oral Performance Instrument (IOPI) and twice from the NPC subjects: before and 2 months after radiation treatment. No significant differences were found in tongue function evaluation for normal or NPC groups in either pre- or post-treatments. However, this study showed that significant decreases in tongue function may not start until 2 months after treatment. ? 2008 Springer Science+Business Media, LLC.Deglutition; Deglutition disorders; Nasopharyngeal carcinoma; Radiation; Tongue endurance; Tongue function; Tongue strength[SDGs]SDG3adult; aged; article; cancer radiotherapy; clinical article; controlled study; female; function test; human; male; muscle function; muscle isometric contraction; muscle strength; nasopharynx carcinoma; priority journal; radiation dose; tongue; Adult; Aged; Carcinoma, Squamous Cell; Deglutition Disorders; Female; Humans; Isometric Contraction; Male; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Staging; Pharyngeal Muscles; Radiotherapy; Time Factorsjournal article10.1007/s00455-007-9128-x182537922-s2.0-44549084094