Li, Yi chunYi chunLiKEH-CHUNG LINChen, Chia lingChia lingChenKAI-PING GRACE YAOYa-ju ChangYA-YUN LEELiu, Chien tingChien tingLiuWEN-SHIANG CHEN2023-05-182023-05-182023-01-0100039993https://scholars.lib.ntu.edu.tw/handle/123456789/631160Objective: To examine the effects of bilateral robotic priming combined with mirror therapy (R-mirr) vs bilateral robotic priming combined with bilateral arm training (R-bilat), relative to the control approach of bilateral robotic priming combined with movement-oriented training (R-mov) in patients with stroke. Design: A single-blind, preliminary, randomized controlled trial. Setting: Four outpatient rehabilitation settings. Participants: Outpatients with stroke and mild to moderate motor impairment (N=63). Interventions: Patients received 6 weeks of clinic-based R-mirr, R-bilat, or R-mov for 90 min/d, 3 d/wk, plus a transfer package at home for 5 d/wk. Main Outcome Measures: Fugl-Meyer Assessment Upper Extremity subscale (FMA-UE), ABILHAND, and Stroke Impact Scale v3.0 scores before, immediately after, and 3 months after treatment as well as lateral pinch strength and accelerometry before and immediately after treatment. Results: The posttest results favored R-mirr over R-bilat and R-mov on the FMA-UE score (P<.05). Follow-up analysis revealed that significant improvement in FMA-UE score was retained at the 3-month follow-up in the R-mirr over R-bilat or R-mov (P<.05). Significant improvements were not observed in the R-mirr over R-bilat and R-mov on other outcomes. Conclusions: Between-group differences were only detected for the primary outcome, FMA-UE. R-mirr was more effective at enhancing upper limb motor improvement, and the effect has the potential to be maintained at 3 months of follow-up.enExercise Movement Techniques | Mirror therapy | Rehabilitation | Repetition Priming | Robotics | Strokejournal article10.1016/j.apmr.2023.02.015369336092-s2.0-85152139137https://api.elsevier.com/content/abstract/scopus_id/85152139137