Tseng W.-C.MEI-HWAN WUChen H.-C.Kao F.-Y.Huang S.-K.2021-01-052021-01-0520161346-9843https://www.scopus.com/inward/record.uri?eid=2-s2.0-84992446006&doi=10.1253%2fcircj.CJ-16-0602&partnerID=40&md5=fa124f0d7c52ee4a0e19d7fe5a18f467https://scholars.lib.ntu.edu.tw/handle/123456789/538266Background: Ventricular fibrillation (VF) is a life-threatening disease that can be remedied by prompt defibrillation. However, data regarding such risk in a general population remain limited. This general population study was to explore the epidemiological profile of VF. Methods and Results: We investigated patients with VF younger than 60 years (average population, 19,725,031) using a national database spanning the period 2000–2010. We identified 3,971 (68.4% male) patients with VF (crude incidence rate: 1.83/100,000). Incidence rates were low in patients younger than 10 years and increased steadily after adolescence. Comorbidities were noted in 2,766 (69.7%) patients, with 2,431 (61%) having cardiac diseases. Over half of the adolescent and young adult patients did not have comorbidities. Among the 838 deaths (mortality rate 21.1%), approximately half (381/838, 45.5%) occurred after arrival at emergency services (ES). The proportion of deaths after arrival at ES relative to total deaths increased sharply to a peak in the 15–19-years age group and thereafter remained stationary. Conclusions: VF patients, with a male dominance, increased after adolescence and were likely to die at presentation to ES. Approximately half of young adults, with high mortality, did not have comorbidities, suggesting underdi-agnosis of underlying primary electrical diseases and the need for implementing automated external defibrillator programs. ? 2016, Japanese Circulation Society. All rights reserved.[SDGs]SDG3adolescent; adult; age; Article; bradycardia; cardiomyopathy; child; comorbidity; congenital heart disease; coronary artery disease; emergency health service; female; gender; heart ventricle fibrillation; human; hypertension; implantable cardioverter defibrillator; incidence; infant; major clinical study; male; middle aged; myocarditis; newborn; preschool child; school child; survival; valvular heart disease; Wolff Parkinson White syndrome; young adult; factual database; pathophysiology; pregnancy; sex difference; United States; Ventricular Fibrillation; Adolescent; Adult; Age Factors; Child; Child, Preschool; Databases, Factual; Female; Humans; Incidence; Infant; Infant, Newborn; Male; Middle Aged; Pregnancy; Sex Factors; United States; Ventricular Fibrillationjournal article10.1253/circj.CJ-16-0602277254942-s2.0-84992446006