2007-12-012024-05-15https://scholars.lib.ntu.edu.tw/handle/123456789/664651摘要：年度分項H計畫的生醫晶片之設計與製作，經過先前幾期製作與各分項計畫之研商，將製作一多功能(multi-function)的檢測晶片，此晶片與其他分項子計畫做整合後可達到皮下植入，並同時監測呼吸與心跳，還有血液中的葡萄糖、膽固醇與CRP(C-reactive protein)蛋白質之含量，並經由無線傳輸技術，將檢測訊號由皮下傳輸至體外。而用以驅動流體之微幫浦方面，在計畫執行當中，與各分項討論過後，將整合 李雨教授實驗室所開發之DEP(Dielectrophoresis)幫浦作為流體驅動與達到血液分離之功用，而圖二與中之設計。整合型檢測晶片實際尺寸在經過各分項討論後，在考慮未來各分項工作整合之相容性，晶片整體架構在初期開發原型時，需限制3公分見方以內之面積大小。<br> Abstract: In Sub-project-H, we will focus on the microfabrication of the bio-chips proposed by the main project. Based on the design and technologies developed by other sub-projects, we will fabricate a multi-function sensing bio-chip. This chip will be implantable, and can detect the basic physical signals such as breath rate and heart-beat rate. Also, this chip can detect glucose and CRP in blood. Wireless communication technologies will be employed. DEP (Dielectrophoresis) micropump will be used to pump fluids (samples) as well as separate plasma and blood cells.微加工微流體生物感測技術高分子材料植入式microfabricationmicrofluidicsbiosensorsPDMSimplantable