LI-NA LEEKWEN-TAY LUHPAN-CHYR YANGChang D.-B.CHONG-JEN YUKo J.-C.Liaw Y.-S.Wu R.-G.2020-12-022020-12-0219940040-6376https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028199940&doi=10.1136%2fthx.49.6.594&partnerID=40&md5=461a1ccd7573f1b90a7de945f2cc8feehttps://scholars.lib.ntu.edu.tw/handle/123456789/524074Background - Conservative treatment of malignant pericardial effusion by intrapericardial instillation of a sclerosing agent may be an alternative to surgery. Methods - Twenty patients with malignant pericardial effusion were treated by ultrasound guided pericardiocentesis and the intrapericardial instillation of mitomycin C. Results - Mitomycin C was effective in controlling the pericardial effusion in 70% of patients without causing side effects, except for pericardial constriction seven months later in one subject. Conclusions - Ultrasound guided intrapericardial instillation of mitomycin C is a suitable alternative in the management of malignant pericardial effusion.[SDGs]SDG3mitomycin c; sclerosing agent; adult; aged; article; cancer; clinical article; clinical trial; drug efficacy; female; human; male; pericardial effusion; pericardiocentesis; priority journal; survival rate; ultrasound; Adult; Aged; Combined Modality Therapy; Drainage; Female; Human; Injections, Intralesional; Lung Neoplasms; Male; Middle Age; Mitomycin; Pericardial Effusionjournal article10.1136/thx.49.6.59480167972-s2.0-0028199940