JANE WANGTIFFANY TING-FANG SHIHHsu J.C.-Y.Li Y.-W.2020-08-062020-08-0620000899-7071https://scholars.lib.ntu.edu.tw/handle/123456789/511277Preoperative mammograms from 395 breast cancers and 132 benign breast lesions were enrolled for this study. The false-negative (FN) rate for breast cancers from preoperative reading was 9.6% with 38 breast cancers missed on mammograms. The statistically significant differences occurred between true-positive (TP) and FN cancers for younger age (P<.025), smaller lesion size (P<.001), denser breast (P<.05), deep retroglandular location (P<.001). None of the FN cancers exhibited calcifications. The FN rate for mammography for benign breast lesions from preoperative reading was 18.9% with 25 lesions misdiagnosed. The statistically significant difference between benign TP and FN lesions occurred for central and subareolar location (P<.025). Exploration of possible factors and imaging features in FN mammograms can help reduce the FN rate for mammography. Copyright (C) 2000 Elsevier Science Inc.[SDGs]SDG3adult; aged; article; Asia; breast calcification; breast cancer; breast lesion; diagnostic error; female; human; major clinical study; mammography; Adult; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Chi-Square Distribution; Diagnosis, Differential; False Negative Reactions; Female; Humans; Mammography; Middle Aged; Retrospective Studiesjournal article10.1016/S0899-7071(00)00184-4111244822-s2.0-0033676372