Alleviation of PM2.5-induced alveolar macrophage inflammation using extract of fermented Chenopodium formosanum Koidz sprouts via regulation of NF-κB pathway

Hsieh, Chen-CheChen-CheHsiehSHU-HAN YUKuo, Hsing-ChunHsing-ChunKuoCheng, Kai-WenKai-WenChengHsu, Cheng-ChihCheng-ChihHsuLin, Yi-PinYi-PinLinKhumsupan, DarinDarinKhumsupanLin, Shin-PingShin-PingLinAngkawijaya, Artik ElisaArtik ElisaAngkawijayaKUAN-CHEN CHENG2023-08-152023-08-152023-08-0203788741https://scholars.lib.ntu.edu.tw/handle/123456789/634542Particulate matter 2.5 (PM2.5) is a dangerous airborne pollutant that has become a global issue due to its detrimental effect on macrophages. Chenopodium formosanum Koidz (Djulis), a native plant from Taiwan well known for its high antioxidant content and is frequently used in ethnomedicine, shows promise as a novel phytomedicine to combat against oxidative stress caused by PM2.5. However, the protective mechanism of Djulis against PM2.5 still remains unclear.enAlveolar macrophage; Anti-inflammatory; Chenopodium formosanum Koidz; Molecular docking; NF-κB pathway; Particulate matterAlleviation of PM2.5-induced alveolar macrophage inflammation using extract of fermented Chenopodium formosanum Koidz sprouts via regulation of NF-κB pathwayjournal article10.1016/j.jep.2023.116980375366442-s2.0-85166540002https://api.elsevier.com/content/abstract/scopus_id/85166540002