Chen, Chung-YenChung-YenChenChen, Ping-HuiPing-HuiChenJIA-KUN CHENTA-CHEN SU2023-01-162023-01-162023-0209296646https://scholars.lib.ntu.edu.tw/handle/123456789/627278This mini-review provides the practice guideline recommendations for ventilation of remodeled negative-pressure isolation wards for COVID-19 Patients. Remodeled "quasi-negative-pressure" isolation wards had been proved a feasible, inexpensive, safe, and effective measure to contain nosocomial outbreaks. We should first determine the minimum required ventilation volume of an isolation ward based on the severity of COVID-19 patients. Mechanical ventilation remains the mainstay for achieving the requirement, while the assistance of recirculation is also helpful. Beyond adequate ventilation volume, the "clean to less-clean" directional airflow remains the golden rule for the solution of indoor ventilation. The virus-laden exhaust should be treated with HEPA/UV device or be kept away from living organisms, buildings, and air inlets.enCOVID-19; Directional airflow; Mechanical ventilation; Negative-pressure isolation wardjournal article10.1016/j.jfma.2022.11.013364766742-s2.0-85143979985https://api.elsevier.com/content/abstract/scopus_id/85143979985