Daptomycin area under the curve to minimum inhibitory concentration ratio by broth microdilution for predicting the outcome of vancomycin-resistant Enterococcus bloodstream infection

YU-CHUNG CHUANGHSIN-YI LINJANN-TAY WANGYang, Jia-LingJia-LingYangLin, Chi-YingChi-YingLinHuang, Sung-HsiSung-HsiHuangYEE-CHUN CHENSHAN-CHWEN CHANG2022-10-282022-10-282022-110753-3322https://scholars.lib.ntu.edu.tw/handle/123456789/624125Different methods are used to determine the minimum inhibitory concentration (MIC) for daptomycin. The threshold is unknown for the free drug area under the concentration-time curve to MIC ratio (fAUC/MIC) of daptomycin using broth microdilution (BMD) to predict outcome of vancomycin-resistant enterococcus (VRE) bacteremia. The MIC testing method which is best for predicting the outcome remains unclear.enDaptomycin; Minimum inhibitory concentration; Mortality; Pharmacodynamic; Vancomycin-resistant enterococci[SDGs]SDG3Daptomycin area under the curve to minimum inhibitory concentration ratio by broth microdilution for predicting the outcome of vancomycin-resistant Enterococcus bloodstream infectionjournal article10.1016/j.biopha.2022.113710361563682-s2.0-85138507776WOS:000864671100001https://scholars.lib.ntu.edu.tw/handle/123456789/623970