3'-Hydroxypterostilbene Potently Suppresses Tumor Growth via Inhibiting the Activation of the JAK2/STAT3 Pathway in Ovarian Clear Cell Carcinoma

Koh, Yen-ChunYen-ChunKohHuang, Wei-ZheWei-ZheHuangNagabhushanam, KalyanamKalyanamNagabhushanamHo, Chi-TangChi-TangHoMIN-HSIUNG PAN2023-11-062023-11-062023-10-2416134125https://scholars.lib.ntu.edu.tw/handle/123456789/636825Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian cancer (EOC) that is associated with higher interleukin-6 (IL-6) levels, and suppression of the Janus kinase 2/Signal transducer and activator of transription 3 (JAK2/STAT3) pathway may contribute to the suppression of this cancer. This study aims to compare the anti-cancer effect of pterostilbene (PSB) and 2'- and 3'-hydroxypterostilbene (2HPSB and 3HPSB, respectively) on the JAK2/STAT3 pathway.en3’-hydoxypterostilbene; JAK2/STAT3; ovarian clear cell carcinoma; pterostilbene; xenograft[SDGs]SDG33'-Hydroxypterostilbene Potently Suppresses Tumor Growth via Inhibiting the Activation of the JAK2/STAT3 Pathway in Ovarian Clear Cell Carcinomajournal article10.1002/mnfr.202300108378761432-s2.0-85174617018https://api.elsevier.com/content/abstract/scopus_id/85174617018