Hsieh W.A.Lin I.-F.Chang W.P.WEI-LI CHENHsu Y.H.MUH-SHY CHEN2020-10-222020-10-2220100033-7587https://www.scopus.com/inward/record.uri?eid=2-s2.0-75149164785&doi=10.1667%2fRR1850.1&partnerID=40&md5=05fb95de8419cf26ba606b2798e5d28ehttps://scholars.lib.ntu.edu.tw/handle/123456789/517824The objective of this study was to assess lenticular changes in a young population years after exposure to protracted long-term low-dose-rate γ radiation in Taiwan. A total of 41 males and 32 females who lived for several years in 60Co-contaminated buildings and were less than 20 years old at their first ophthalmological examination in 1998 had a similar examination 4.7 ± 0.5 years later. Lens opacities were examined by slit-lamp biomicroscopy and were scored by the Lens Opacities Classification System III (LOCS III) and a modified subclinical minor focal lens defect (FLD) system. The FLD scores for both eyes were significantly higher than those in the 1998 examinations. Increases in FLD scores compared to those for unexposed subjects occurred particularly in the anterior lens cortex. Increases in FLD scores were also significantly associated with the amount of previous protracted radiation exposure. An exposure-dependent increase in lens opacities was noted years after individuals relocated from the radiocontaminated environment, suggesting that late lenticular changes persisted and progressed in individuals with previous protracted radiation exposure. ? 2010 by Radiation Research Society. All rights of reproduction in any form reserved.[SDGs]SDG3cobalt 60; adolescent; adult; age; article; biomicroscopy; building; cataract; child; clinical assessment tool; controlled study; correlation analysis; disease classification; female; Focal Lens Defect System; gamma radiation; human; infant; lens; Lens Opacities Classification System; major clinical study; male; preschool child; priority journal; radiation exposure; radiation hazard; risk factor; school child; slit lamp; Taiwan; Adolescent; Adult; Child; Child, Preschool; Cobalt Radioisotopes; Corneal Opacity; Dose-Response Relationship, Radiation; Environmental Exposure; Female; Gamma Rays; Housing; Humans; Male; Radioactive Pollutants; Taiwanjournal article10.1667/RR1850.1200958522-s2.0-75149164785