CHANG-FENG DAI2018-09-102018-09-102006http://www.scopus.com/inward/record.url?eid=2-s2.0-33748779855&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/322447Four new cespitularane diterpenes, cesputularins I-L (1-4), two new norverticillane norditerpenes, cespitularins M and N (5 and 6), two new verticillane diterpenes, cespitularins O and P (7 and 8), a new norditerpene, cespitularin Q (9) (having a novel carbon skeleton), a new xenicane diterpene, cespitolide (10), and two new secosteroids, 3β,11-dihydroxy-5β, 6β-epoxy-9,11-secocholestan-9-one (11) and 3β,11-dihydroxy-5β, 6β-epoxy-9,11-secogorgostan-9-one (12), were isolated from the methylene chloride solubles of the Formosan soft coral Cespitularia hypotentaculata Roxas. The structures were elucidated by extensive spectroscopic analysis, and their cytotoxicity against selected cancer cells was measured in vitro. ? 2006 American Chemical Society and American Society of Pharmacognosy.[SDGs]SDG3[SDGs]SDG143beta,11 dihydroxy 5beta,6beta epoxy 9,11 secocholestan 9 one; 3beta,11 hydroxy 5beta,6beta epoxy 9,11 secogorgostan 9 one; cespitolide; Cespitularia hypotentaculata extract; cespitularin i; cespitularin j; cespitularin k; cespitularin l; cespitularin m; cespitularin n; cespitularin o; cespitularin p; cespitularin q; dichloromethane; diterpenoid; natural product; norditerpenoid derivative; secosteroid; unclassified drug; article; carbon nuclear magnetic resonance; chemical structure; controlled study; coral; nonhuman; proton nuclear magnetic resonance; Animals; Anthozoa; Antineoplastic Agents; Computer Simulation; Diterpenes; Drug Screening Assays, Antitumor; Leukemia P388; Mice; Molecular Conformation; Molecular Structure; Secosteroids; Taiwan; Tumor Cells, Cultured; Alcyonaceajournal article10.1021/np05054652-s2.0-33748779855WOS:000240020000014