E. L. WuT. D. ChiuehJ. H. ChenTZI-DAR CHIUEHJYH-HORNG CHEN2018-09-102018-09-102014-09http://scholars.lib.ntu.edu.tw/handle/123456789/388987Purpose: In this study multiple-frequency excitation wideband MRI (ME-WMRI), a technique designed to acquire simultaneously excited images without blurring was proposed. Methods: ME-WMRI consists of (a) a coherent acquisition sequence that applies refocusing gradient during readout to mitigate signal dephasing, and (b) a signal enhancement procedure that further reduces image blurring. This two-step method was tested on phantom imaging andin vivo imaging with up to 3.84 pixel blur. Results: Imaging results in both phantom andin vivo show that the lost details were successfully restored in the blur-mitigated images, and the accelerated images were comparable to standard images. Conclusions: The proposed ME-WMRI method can effectively undo the image blurring, and thus removes the limitation on fast simultaneous multislice MRI systems with a large acceleration factor. ? 2014 American Association of Physicists in Medicine.blur; coherent acquisition; dephasing; ME-WMRI; signal enhancement[SDGs]SDG3Image enhancement; Phantoms; blur; Coherent acquisition; Dephasing; ME-WMRI; Signal enhancement; Magnetic resonance imaging; article; attenuation; excitation; Fourier transformation; human; integration; mathematical model; multiple frequency excitation wideband; nuclear magnetic resonance imaging; nuclear magnetic resonance scanner; radiological parameters; signal detection; waveform; algorithm; anatomy and histology; animal; artifact; brain; devices; image enhancement; image quality; mouse; pig; procedures; signal noise ratio; tail; three dimensional imaging; Algorithms; Animals; Artifacts; Brain; Humans; Image Enhancement; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Mice; Phantoms, Imaging; Signal-To-Noise Ratio; Swine; Tailjournal article10.1118/1.48935022-s2.0-84930370354WOS:000342204800037