陸坤泰2006-07-262018-07-122006-07-262018-07-122003-07-31http://ntur.lib.ntu.edu.tw//handle/246246/27342From December 2002 to February 2003, 15 isolates of pandrug-resistant unidentified Acinetobacter species were recovered from seven patients with nosocomial infections or colonizations treated at different wards or intensive care units at the National Taiwan Univer sity Hospital. These isolates, which were glucose- and lactose-non-acidifier s, failed to recognize to the species level using three commercial identification systems: the Vitek GNI, API 20NE system (bioMerieux, Marcy L’Etoile, France) and the Phoenix System (Becton-Dickinson, Sparks, Md.), and 16S rRNA gene sequence analysis. However , 16S-23S rRNA intergenic spacer PCR-restr iction fragment length polymorphism profiles and the sequence analysis of these isolates both identified as A. baumannii. All these isolates were uniformly resistant to ampicillin-sulbactam (MICs, 128->128 mg/ml), ceftazidime (MICs, 64->128 mg/ml), piperacillin-tazobactam (MICs, 128->128 mg/ml), cefepime (MICs, 16-32 mg/ml), aztreonam (MICs, 64-128 mg/ml), ciprofloxacin (MICs, 64-128 mg/ml), trovafloxacin (MICs, 8-16 mg/ml), moxifloxacin (MICs, 4 mg/ml), garenoxacin (MICs, 16-32 mg/ml), amikacin (MICs, >128 mg/ml), imipenem (MICs, 8-16 mg/ml), and meropenem (MICs, 128->128 mg/ml). The identity of the pulsed-field gel electrophoresis patterns and antibiotypes among these isolates from the same patients with an interval of 4-8 weeks and different patients indicated that this pandrug-resistant A.baumannii with unusual phenotype could have long-term per sistence in humans and has widely disseminated at the hospital.application/pdf165592 bytesapplication/pdfzh-TW國立臺灣大學醫學院檢驗醫學科journal articlehttp://ntur.lib.ntu.edu.tw/bitstream/246246/27342/1/912314B002172.pdf