Liu C.-C.Hwu H.-G.YEN-NAN CHIULai M.-C.Tseng H.-H.2021-06-292021-06-29201092966462-s2.0-77955506834https://scholars.lib.ntu.edu.tw/handle/123456789/567043Early identification of subjects at risk of developing psychosis is the key to early intervention. A prospective study on the psychopathological progress from prodromal state to full-blown psychosis was initiated in Taiwan in 2006. However, the clinical entity of our interests is ill-defined; therefore, recruitment of at risk subjects to participate in studies requires innovation. In November 2006, the study team launched a special clinic for cognitive and perceptual disturbance. In the first year, 142 subjects, mostly aged 16-30 year olds, made an appointment for this special clinic. More than 20 tentative diagnoses were made. Seventy-six subjects with a gradient of clinical severity were eligible for enrollment, and 68 gave informed consent to participate in the research. It seems that setting up a special clinic to provide a service for at risk subjects, combined with certain campaigns, could facilitate their engagement in a longitudinal prospective study for early psychosis. ? 2010 Formosan Medical Association & Elsevier.[SDGs]SDG3antidepressant agent; anxiolytic agent; neuroleptic agent; sulpiride; adolescent; adult; anxiety disorder; article; bipolar disorder; clinical trial; cognitive defect; dysthymia; early intervention; eating disorder; emotional disorder; female; human; low drug dose; major clinical study; male; mental deficiency; mental health center; obsessive compulsive disorder; organic brain syndrome; perception disorder; psychosis; schizophrenia; sleep disorder; social phobia; stress; Taiwan; age distribution; early diagnosis; mental disease; prospective study; psychosis; research; risk; schizophrenia; time; Adolescent; Adult; Age Distribution; Early Diagnosis; Female; Humans; Male; Prospective Studies; Psychopathology; Psychotic Disorders; Research; Risk; Schizophrenia; Taiwan; Time Factors; Young Adultjournal article10.1016/S0929-6646(10)60089-720654794