MING-TAI LINChang C.-H.Hsieh W.-C.Chang C.-E.Chang Y.-M.Chen Y.-C.Hsu J.-Y.Huang Y.-L.Ma J.-Y.Sun L.-C.Wu C.-S.Yeh S.-Z.Fang W.-Q.CHUN-AN CHENSHUENN-NAN CHIUCHUN-WEI LUJOU-KOU WANGMEI-HWAN WU2020-12-212020-12-2120141011-6842https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907290204&partnerID=40&md5=d8e5fad79ed87284f0d6bd18dfc1ae30https://scholars.lib.ntu.edu.tw/handle/123456789/529299Background: The measurements of coronary diameters, usually obtained by 2-dimentsional echocardiography, play important roles oin the management and follow-up of Kawasaki disease (KD). However, in Taiwan, domestic normgrams and a Z-score calculator for coronary artery diameters are still not available. Methods: Echocardiography was performed on 412 healthy children younger than 6 years of age. The appropriate exponential regression model was fitted to correspond with body surface area (BSA). The computed Z-scores of all subjects were also tested for normal distribution. Results: Using the model ln (measurement) = β1 + β2 x ln (BSA), the adjusted R2 values were 0.611 and 0.484 for themodels of the left main coronary artery (LMCA) and the right (RCA), respectively. Analysis of computed Z-score distribution showed acceptable goodness of fit for a normal distribution [p = 0.90 (LMCA); p = 0.17 (RCA)]. Conclusions: We have established reference ranges for the coronary artery diameters in Taiwanese children younger than 6 years of age. The regression equations and Z-score calculators for the LMCA and RCA provide an objective determination of coronary dilatation in a large population, which is important for the care and medical management of KD patients in Taiwan.[SDGs]SDG3artery diameter; Article; body surface; child; color ultrasound flowmetry; coronary artery; coronary artery circumflex branch; coronary artery diameter; coronary artery dilatation; female; follow up; human; left anterior descending coronary artery; left coronary artery; male; normal human; preschool child; real time ultrasound scanner; right coronary artery; Taiwanese; transthoracic echocardiography; two dimensional echocardiographyCoronary diameters in Taiwanese children younger than 6 years old: Z-score regression equations derived from body surface areajournal article2-s2.0-84907290204