Lin, Ting-WeiTing-WeiLinYA-CHIAO HUYAO-HSU YANGYIN-HSIU CHIENNI-CHUNG LEEHSIN-HUI YUBOR-LUEN CHIANGLI-CHIEH WANG2022-03-172022-03-172021-11-1316841182https://scholars.lib.ntu.edu.tw/handle/123456789/597715We reported a patient with autoimmunity (multiple sclerosis), immunodeficiency (hypogammaglobulinemia with severe infections), enteropathy (diarrhea with intestinal inflammation), splenomegaly, lymphadenopathy and lymphocytic infiltration of non-lymphoid organs (lung, gut and brain). The patient was found to have a heterozygous mutation in cytotoxic T lymphocyte antigen-4, and had excellent response to abatacept.enAbatacept; Cytotoxic T lymphocyte antigen-4; Multiple sclerosis; Primary immunodeficiency[SDGs]SDG3journal article10.1016/j.jmii.2021.10.009348240192-s2.0-85119667082https://scholars.lib.ntu.edu.tw/handle/123456789/589870