Wang, F.-N.F.-N.WangHuang, T.-Y.T.-Y.HuangLin, F.-H.F.-H.LinChuang, T.-C.T.-C.ChuangChen, N.-K.N.-K.ChenChen, C.-Y.C.-Y.ChenKwong, K.K.K.K.KwongHSIAO-WEN CHUNG2018-09-102018-09-102005http://www.scopus.com/inward/record.url?eid=2-s2.0-27644579499&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/316495A technique suitable for diffusion tensor imaging (DTI) at high field strengths is presented in this work. The method is based on a periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) k-space trajectory using EPI as the signal readout module, and hence is dubbed PROPELLER EPI. The implementation of PROPELLER EPI included a series of correction schemes to reduce possible errors associated with the intrinsically higher sensitivity of EPI to off-resonance effects. Experimental results on a 3.0 Tesla MR system showed that the PROPELLER EPI images exhibit substantially reduced geometric distortions compared with single-shot EPI, at a much lower RF specific absorption rate (SAR) than the original version of the PROPELLER fast spin-echo (FSE) technique. For DTI, the self-navigated phase-correction capability of the PROPELLER EPI sequence was shown to be effective for in vivo imaging. A higher signal-to-noise ratio (SMR) compared to single-shot EPI at an identical total scan time was achieved, which is advantageous for routine DTI applications in clinical practice. © 2005 Wiley-Liss, Inc.Diffusion tensor imaging; EPI; Geometric distortions; PROPELLER imaging; Specific absorption rateBiomedical signal processing; Clustering algorithms; Diffusion; Geometry; Magnetic resonance imaging; Propellers; Signal to noise ratio; Space flight; Tensors; Clinical practices; Correction schemes; Fast spin echos; Geometric distortion; High field strengths; K-space trajectories; Phase corrections; Specific absorption rate; Diffusion tensor imaging; analytic method; analytical error; article; clinical practice; comparative study; contrast enhancement; diffusion tensor imaging; geometry; image reconstruction; in vivo study; nuclear magnetic resonance imaging; sensitivity and specificity; signal noise ratioPROPELLER EPI: An MRI technique suitable for diffusion tensor imaging at high field strength with reduced geometric distortionsjournal article10.1002/mrm.206772-s2.0-27644579499