廖秀娟2006-07-252018-06-292006-07-252018-06-292005http://ntur.lib.ntu.edu.tw//handle/246246/10792砷污染對人類健康及環境造成潛在的風險。當生物體暴露於砷時，會造成多種不 同的毒性效應，例如：立即性的死亡，或緩慢的引發癌症效應。本研究計畫之主要目 標，將建立分子生物指標用來監測水生態系統之砷暴露。此外，砷於不同的魚組織的 濃度分布，以及其生化效應將被探討。 本研究計畫將分為二年執行，將延續前一年的研究成果，繼續水生態系統中砷暴 露之分子生化效應之相關研究。研究成果將有助於建立水生態系統中砷之監測及警示 系統，並有助於更準確的風險評估。Arsenic contaminants cause a high potential risk to human health and the environment. Exposure of humans and animals to arsenic results in a variety of toxic effects ranging from immediate mortality to slow process of carcinogenesis. The primary goal of this proposal is to develop molecular biomarkers for monitoring arsenic exposure in aquatic ecosystems. In addition, the tissue distribution of arsenic and the corresponding biochemical effects in tilapia fish will be investigated. This 2-year grant proposal will continue the work from previous year to study arsenic induced biochemical effects in aquatic organisms. The studies employed in this proposal will reflect the specific toxic effect of arsenic and reveal fundamental relationships between chemical structures and biological activity. The molecular biomarker developed in this study may serve an early warning system for the detection and monitoring arsenic exposure in aquatic ecosystems. This may contribute to a better accurate risk assessment.application/pdf248545 bytesapplication/pdfzh-TW國立臺灣大學生物環境系統工程學系暨研究所砷污染生化效應分子生物指標arsenic exposurebiomarkerbiochemical effect[SDGs]SDG3reporthttp://ntur.lib.ntu.edu.tw/bitstream/246246/10792/1/932313B002075.pdf