Antidepressant-like effects of water extract of Cordyceps militaris (Linn.) Link by modulation of ROCK2/PTEN/Akt signaling in an unpredictable chronic mild stress-induced animal model

Lin, Yu-EnYu-EnLinChen, Yi-ChunYi-ChunChenKUAN-HUNG LUHuang, Yun-JuYun-JuHuangPanyod, SuraphanSuraphanPanyodLiu, Wei-TingWei-TingLiuYang, Shu-HuiShu-HuiYangLu, Yun-ShengYun-ShengLuChen, Mei-HsingMei-HsingChenLEE-YAN SHEEN2022-01-122022-01-122021-08-1003788741https://scholars.lib.ntu.edu.tw/handle/123456789/592184Cordyceps militaris (Linn.) Link (CM) is a medicinal mushroom traditionally used in tonics for treating several neurological disorders, including epilepsy and anxiety, in Asia. Reports have shown that CM has anti-inflammatory and anti-oxidative effects and may be beneficial for depression management.enCordyceps militaris; Depression; Neurodegeneration; ROCK2/PTEN/Akt pathway; Unpredictable chronic mild stressAntidepressant-like effects of water extract of Cordyceps militaris (Linn.) Link by modulation of ROCK2/PTEN/Akt signaling in an unpredictable chronic mild stress-induced animal modeljournal article10.1016/j.jep.2021.114194339749452-s2.0-85105782822WOS:000660251400006https://scholars.lib.ntu.edu.tw/handle/123456789/571315https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105782822&doi=10.1016%2fj.jep.2021.114194&partnerID=40&md5=3bafa947416c44df465a738ceb627b46