Chen C.-Y.WOEI TSAYJIH-LUH TANGHWEI-FANG TIENYEE-CHUN CHENSHAN-CHWEN CHANGPO-REN HSUEH2020-03-272020-03-2720100950-2688https://scholars.lib.ntu.edu.tw/handle/123456789/480108All bacterial isolates from 7058 patients admitted to haemato-oncology wards at National Taiwan University Hospital between 2002 and 2006 were characterized. In total 1307 non-duplicate bloodstream isolates were made from all patients with haematological malignancy; 853 (65%) of these were from neutropenic patients. Gram-negative bacteria predominated (60%) in neutropenic isolates with Escherichia coli (12%), Klebsiella pneumoniae (10%), Acinetobacter calcoaceticus-baumannii complex (6%), and Stenotrophomonas maltophilia (6%) the most frequent. Coagulase-negative staphylococci (19%) and Staphylococcus aureus (4%) were the most common Gram-positive pathogens. Resistance to ciprofloxacin was found in 50% of E. coli and 20% of K. pneumoniae isolates from neutropenic patients. Extensively drug-resistant A. calcoaceticus-baumannii complex and vancomycin-resistant enterococci were also found during the study period. Emerging antimicrobial resistant pathogens are an increasing threat to neutropenic cancer patients. Copyright ? 2009 Cambridge University Press.[SDGs]SDG3amikacin; aztreonam; cefepime; cefotaxime; ciprofloxacin; colistin; gentamicin; imipenem; levofloxacin; meropenem; moxifloxacin; sultamicillin; timentin; vancomycin; Acinetobacter baumannii; Acinetobacter calcoaceticus; acute granulocytic leukemia; acute lymphoblastic leukemia; antibiotic prophylaxis; antibiotic resistance; aplastic anemia; article; bacterium isolation; bloodstream infection; cancer patient; Candida albicans; Candida parapsilosis; Candida tropicalis; chronic lymphatic leukemia; chronic myeloid leukemia; Enterobacter cloacae; Enterococcus faecalis; Enterococcus faecium; Escherichia coli; febrile neutropenia; hematologic malignancy; hospital admission; human; Klebsiella oxytoca; Klebsiella pneumoniae; major clinical study; mortality; multiple myeloma; myelodysplastic syndrome; nonhodgkin lymphoma; oncology ward; Proteus mirabilis; Pseudomonas aeruginosa; Staphylococcus aureus; Staphylococcus epidermidis; Stenotrophomonas maltophilia; Acinetobacter baumannii; Acinetobacter Infections; Bacteremia; Escherichia coli Infections; Gram-Negative Bacterial Infections; Hematologic Neoplasms; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Neutropenia; Staphylococcal Infections; Stenotrophomonas maltophilia; Taiwanjournal article10.1017/S0950268809991208199416862-s2.0-77953611920