Huang Y.-H.HSIAO-SANG CHUFUNG-RONG HUI-JONG WANGYU-CHIH HOUWEI-LI CHEN2020-10-222020-10-2220080277-3740https://www.scopus.com/inward/record.uri?eid=2-s2.0-40449114177&doi=10.1097%2fICO.0b013e318156d572&partnerID=40&md5=5d90e738502f3924ca0fe242b34c1255https://scholars.lib.ntu.edu.tw/handle/123456789/517833Purpose: To report an unusual case of advancing wavelike epitheliopathy that recurred at a site opposite to the initially affected site. Methods: Single interventional case report. This report describes a 50-year-old woman who presented with advancing, wavelike epitheliopathy of her right eye that lasted 2 months. Results: Slit-lamp biomicroscopy revealed wavy, coarse, irregular epithelium extending from the upper limbus to the central cornea. Confocal microscopy revealed abnormal basal epithelial cells with a loss of cellular borders and hyperreflective nuclei. Application of 1% silver nitrate solution onto the superior limbus effectively treated this condition. However, wavy, irregular epithelium was observed 2 years later in the lower limbus. Conclusions: Advancing wavelike epitheliopathy can occur from the lower limbus and recur from the opposite side of the initial presentation, even after successful treatment with 1% silver nitrate solution. Copyright ? 2007 by Lippincott Williams & Wilkins.[SDGs]SDG3silver nitrate; article; case report; confocal microscopy; cornea disease; cornea epithelium; cornea limbus; debridement; drug effect; female; human; middle aged; pathology; recurrent disease; Corneal Diseases; Debridement; Epithelium, Corneal; Female; Humans; Limbus Corneae; Microscopy, Confocal; Middle Aged; Recurrence; Silver Nitratejournal article10.1097/ICO.0b013e318156d572182459782-s2.0-40449114177