檢驗醫學科Hsueh, Po-RenPo-RenHsuehHawkey, Peter MichaelPeter MichaelHawkey2008-12-082018-07-122008-12-082018-07-122007http://ntur.lib.ntu.edu.tw//handle/246246/89471The selection of antimicrobial agents in the 2006 Guidelines (consensus statement) on Empiric Therapy for Complicated Intra-Abdominal Infections ( IAIs) in Asia was based on resistance and epidemiological data from the Asian region. In these 2006 guidelines, single agent therapy using the beta-lactam/beta-lactamase inhibitors ampicillin/sulbactam or cefoperazone -sulbactam is recommended for mild-to- moderate cases, while piperacillin- tazobactam is recommended for high-severity cases. When using carbapenems, ertapenem is recommended for mild-to-moderate cases, while imipenem and meropenem are recommended for high-severity cases. For combination regimes , two types of agents are recommended: cephalosporin-based and monobactam- based. For mild-to- moderate cases, a third generation cephalosporin plus metronidazole is recommended. For high-severity cases, a third or fourth generation cephalosporin plus metronidazole+ /- amikacin is recommended. For the monobactam-based regimen , aztreonam plus metronidazole is recommended for high- severity cases only. (c) 2007 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.en-USintra-abdominal infectionsantimicrobial therapyAsiaconsensus