CHIEN-HWA CHANGNAI-KUAN CHOURON-BIN HSUSHU-HSUN CHUPOH-HUANG LEESHOEI-SHEN WANG2020-03-062020-03-0620071682-606Xhttp://www.airitilibrary.com/Publication/alDetailedMesh?DocID=10116788-200702-40-1-25-29-ahttps://scholars.lib.ntu.edu.tw/handle/123456789/472908Combined heart and kidney transplantation (CHRT) has been an acceptable therapeutic option with a lower allograft rejection rate than isolated heart or kidney transplantation. Herein we present a patient who received CHRT using a single donor at a medical center in 1995. This is the first case of CHRT in Taiwan. After ten years follow up, no renal rejection but one episode of cardiac rejection has been noted. Cardiac function and renal function have remained normal. We reviewed the literature about immunology and post-transplantation complications of CHRT. In conclusion, CHRT is a feasible procedure for patients with end-stage cardiac and renal failure. This patient, with only one episode of rejection has attained long-term survival with fair cardiac and renal function.zhcombined heart and kidney transplantationpost-transplantationrejectionlong-term survivaljournal article10.29833/FJS.200702.0004