2007-08-012024-05-15https://scholars.lib.ntu.edu.tw/handle/123456789/662403Abstract: White spot syndrome virus (WSSV) infection results in white spot disease in crustaceans and is causing considerable economic losses in shrimp farming industry worldwide. Despite of its stern condition and past research efforts desiring to find cures for the disease, an effective vaccine or curing medicine is still missing. Studying the interaction between WSSV and host cells will not only broaden our knowledge on this virus but also help us find effective regimens for this disease. The objectives of this sub-project are to establish the structural interactome network maps of viral proteins and viral-host cell proteins. With future aquacultural applications in our mind, specific efforts will be directed to find receptors for WSSV entrance into host cells. In addition, if WSSV infection induces stress responses after entering shrimp host cells and their possibilities for clinical manipulation will be analyzed.white spot syndrome virus (WSSV)interactomeyeast two-hybrid screeningstress responsesystem biology