Chen, Kow-TongKow-TongChenTwu, Shiing-JerShiing-JerTwuChang, Hong-JenHong-JenChangLin, Ruey-ShiungRuey-ShiungLin2009-05-272018-06-292009-05-272018-06-292003http://ntur.lib.ntu.edu.tw//handle/246246/160571Objectives. This study sought to identify the risk factors associated with an outbreak of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) among Filipino laborers in Taiwan. Methods. Forty-six SJS/TEN patients were matched to 92 controls according to month of arrival in Taiwan, sex, and age. Results. The odds ratio for development of SJS/TEN was 9.5 (95% confidence interval [Cl]=3.9, 23.9) among workers who had used both metronidazole and mebendazole sometime in the preceding 6 weeks. In addition, a gradient increase in the occurrence of SJS/TEN was found with an increasing level of exposure to metronidazole. Conclusions. This outbreak highlights the risk of SJS/TEN resulting from the use of both metronidazole and mebendazole and the need for control measures.application/pdf104571 bytesapplication/pdfen-US[SDGs]SDG3mebendazole; metronidazole; adult; amebiasis; article; dysentery; epidemic; ethnic group; female; human; major clinical study; male; prognosis; protozoal infection; race difference; risk factor; Stevens Johnson syndrome; Taiwan; toxic epidermal necrolysisjournal article10.2105/AJPH.93.3.489http://ntur.lib.ntu.edu.tw/bitstream/246246/160571/1/52.pdf