Wan-Ting HuangPING-ING LEELUAN-YIN CHANGCHUAN-LIANG KAOLI-MIN HUANGCHUN-YI LUJONG-MIN CHENLee, Chin-YunChin-YunLee2021-11-292021-11-292010-1216841182https://scholars.lib.ntu.edu.tw/handle/123456789/588155Epidemic pleurodynia is seldom reported in Southeast Asia and there has been no report from Taiwan. We conducted a retrospective chart review of children = 18 years of age in the National Taiwan University Hospital from January 1 to December 31, 2005. Epidemic pleurodynia was defined as an acute illness characterized by sharp localized pain over the chest or upper abdomen. Patients with known heart diseases or pulmonary consolidations were excluded. In total, 28 patients met the case definition of epidemic pleurodynia. Coxsackievirus B3 (CB3) was isolated in 15 (60%) of the 25 throat swab specimens. Four (14%) of the 28 patients presented chest wall tenderness and only one (6%) of the 18 patients tested had an elevated creatinine kinase level. Twenty-one (75%) of the 28 patients described pleuritic chest pains and 10 (45%) of the 22 chest radiographies exhibited pulmonary infiltrates or pleural effusions. Six patients were observed with tonsillar exudates and one was confirmed to have a CB3 urinary tract infection. The clinical features and radiological findings suggest that CB3-associated epidemic pleurodynia might be a disease of the pleura and occasionally spreads to nearby tissues, resulting in chest wall myositis, pulmonary infiltrates and myopericarditis.enChest pain | Coxsackievirus B3 | Epidemic pleurodynia | Exudative tonsillitis | PleuritisChest pain; Coxsackievirus B3; Epidemic pleurodynia; Exudative tonsillitis; Pleuritis[SDGs]SDG3aspartate aminotransferase; creatine kinase; adolescent; adult; article; aspartate aminotransferase blood level; Bornholm disease; clinical article; Coxsackie virus B; Coxsackie virus infection; ECG abnormality; enzyme blood level; exudate; female; fever; headache; human; leukocyte count; lung infiltrate; male; medical record review; mouth ulcer; myositis; pericarditis; peritonsillar abscess; pleura effusion; rash; Taiwan; thorax pain; thorax radiography; thorax wall; throat culture; university hospital; upper abdominal pain; urinary tract infection; virus isolation; Adolescent; Child; Child, Preschool; Coxsackievirus Infections; Enterovirus B, Human; Epidemics; Female; Hospitals, University; Humans; Infant; Infant, Newborn; Male; Pharynx; Pleurisy; Pleurodynia, Epidemic; Taiwan; Tonsillitis; Urinary Tract Infectionsjournal article10.1016/S1684-1182(10)60079-5211959792-s2.0-78650720050https://scholars.lib.ntu.edu.tw/handle/123456789/539569