CHUNG-I CHANGKe Y.-C.JOU-KOU WANGMEI-HWAN WU2021-01-052021-01-0520050929-6646https://www.scopus.com/inward/record.uri?eid=2-s2.0-24944508710&partnerID=40&md5=47754a660a84e24d6de5c1d970ab9313https://scholars.lib.ntu.edu.tw/handle/123456789/538428Background and Purpose: Currently, prosthetic selection for aortic valve replacement is still debatable in pediatric patients with aortic valve disease. Ross procedure is a time-consuming and demanding technique which may produce good results. This study assessed the results obtained with various methods of right ventricle outflow tract (RVOT) reconstruction in patients receiving Ross procedure. Methods: From September 1996 to December 2003, 13 pediatric patients underwent Ross procedure for aortic valve disease. Their ages ranged from 1 month to 17 years (mean, 6.29 ± 3.62 years; median, 7 years) and 2 patients were less than 1 year of age. Previous procedures in these patients included balloon dilation of the aortic valve in 10 and surgical aortic valvuloplasty in 2. RVOT was reconstructed with heterografts in 3, homografts in 3 or without extracardiac conduits in 7. Results: There was 1 in-hospital death (7.7%) and 1 late death from a non-cardiac cause. One patient developed infective endocarditis with periaortic abscess 2 weeks after the Ross procedure. Eleven patients were followed for a mean of 3.3 years (range, 8 months to 8 years). There was no significant pressure gradient across the neoaorta. Severe stenosis developed gradually in 3 patients who had RVOT reconstruction with heterograft conduits. All 3 had received RVOT redo operation. None of the patients who received RVOT reconstruction without extracardiac conduits had significant pulmonary stenosis but 6 had regurgitation (nil 1, mild 3, moderate 3). No redo operation was required during follow-up (range, 8 months to 4 years). All of the 11 survivors were in New York Heart Association functional class I. Conclusions: This study found satisfactory results of Ross procedure in pediatric aortic valve disease. RVOT reconstruction without extracardiac conduit is a feasible alternative despite the availability of homograft.[SDGs]SDG3adolescent; allograft; aorta stenosis; aorta valve disease; aorta valve stenosis; article; balloon dilatation; child; clinical article; controlled study; death; disease severity; female; follow up; heart right ventricle outflow tract; heart ventricle septum defect; human; infant; male; mitral valve commissurotomy; plastic surgery; valvuloplasty; aorta valve; aorta valve regurgitation; aorta valve stenosis; heart surgery; preschool child; pulmonary artery; transplantation; Adolescent; Aortic Valve; Aortic Valve Insufficiency; Aortic Valve Stenosis; Cardiac Surgical Procedures; Child; Child, Preschool; Female; Humans; Infant; Male; Pulmonary Arteryjournal article160918252-s2.0-24944508710