Overexpression of FLT3-ITD driven by spi-1 results in expanded myelopoiesis with leukemic phenotype in zebrafish

Lu J.-W.HSIN-AN HOUHsieh M.-S.HWEI-FANG TIENLIANG-IN LIN2020-06-162020-06-1620160887-6924https://scholars.lib.ntu.edu.tw/handle/123456789/502658[SDGs]SDG3Flt3 ligand; genomic DNA; nucleophosmin; transcription factor Sp1; CD135 antigen; oncoprotein; proto-oncogene protein Spi-1; transactivator protein; acute myeloblastic leukemia; cancer prognosis; DNA determination; embryo development; gene duplication; gene mutation; gene overexpression; hematopoiesis; internal tandem duplication; Letter; leukemia; myelopoiesis; nonhuman; phenotype; priority journal; transgenic fish; zebra fish; animal; embryology; genetics; metabolism; myelopoiesis; physiology; transgenic animal; Animals; Animals, Genetically Modified; fms-Like Tyrosine Kinase 3; Myelopoiesis; Phenotype; Proto-Oncogene Proteins; Trans-Activators; ZebrafishOverexpression of FLT3-ITD driven by spi-1 results in expanded myelopoiesis with leukemic phenotype in zebrafishletter10.1038/leu.2016.132272712272-s2.0-84976308231