Ting Y.-T.CHUN-YI LUPEI-LAN SHAOPING-ING LEEJONG-MIN CHENPO-REN HSUEHLI-MIN HUANGLUAN-YIN CHANG2020-03-272020-03-2720151684-1182https://scholars.lib.ntu.edu.tw/handle/123456789/479808To investigate the etiologies and antibiotic susceptibility of community-acquired bacteremia in infants in a medical center in northern Taiwan. Methods: We conducted a retrospective analysis of all blood cultures from infants in the National Taiwan University Hospital from 2002 to 2011 to find community-acquired bacteremia. Common pathogens, antibiotic resistance, and outcome were analyzed. Results: During the study period, 25,628 blood cultures were collected, and 3.4% of the cultures were positive, of which 15.9% were categorized as community-acquired bacteremia. In the age group of 0-6-days, the leading causative organisms were group B streptococcus (41.7%) and Escherichia coli (30.6%). In the 7-90-days and 4-6-months groups, the most common pathogens were E. coli (44.1%, 45.5%, respectively) and group B streptococcus (32.4%, 13.6%, respectively). For infants aged 7-12 months, the most common pathogens were Salmonella species (51.1%) and E. coli (12.8%). The overall mortality rate of community-acquired bacteremia was 6%. Urinary tract infection was the concomitant diagnosis among 52.4% of infants with E. coli bacteremia. Meningitis was found in 33.3% of infants with group B streptococcus bacteremia. Listeria monocytogenes bacteremia was identified in three infants, one of whom had meningitis. Penicillin resistance was found in 4% of group B streptococcus and ampicillin resistance in 71% of E. coli. Conclusion: Our study provides updated etiological data on community-acquired bacteremia in infants in northern Taiwan. Group B streptococcus and E. coli remained the leading pathogens in infants aged 6 months or younger and Salmonella species for those older than 6 months. ? 2013.[SDGs]SDG3ampicillin; cefazolin; cefmetazole; cefotaxime; ciprofloxacin; cotrimoxazole; gentamicin; age distribution; antibiotic resistance; antibiotic sensitivity; Article; bacteremia; bacterial meningitis; blood culture; community acquired infection; epidemic; Escherichia coli; female; human; infant; Listeria monocytogenes; male; mortality; newborn; nonhuman; penicillin resistance; Salmonella; Streptococcus agalactiae; Taiwan; university hospital; age; bacteremia; bacterium; classification; Community-Acquired Infections; incidence; isolation and purification; microbial sensitivity test; microbiology; prevalence; retrospective study; survival analysis; Academic Medical Centers; Age Factors; Bacteremia; Bacteria; Community-Acquired Infections; Drug Resistance, Bacterial; Female; Hospitals, University; Humans; Incidence; Infant; Infant, Newborn; Male; Microbial Sensitivity Tests; Prevalence; Retrospective Studies; Survival Analysis; Taiwanjournal article10.1016/j.jmii.2013.10.005242916172-s2.0-84938286832