2024-05-182024-05-1864752https://scholars.lib.ntu.edu.tw/handle/123456789/718975李弘元教授為國立臺灣大學醫學院內科教授，並任職於臺大醫院內科部新陳代謝科主治醫師，為糖尿病與代謝疾病流行病學及孕期代謝異常研究領域的重要學者之一。李教授畢業於國立臺灣大學醫學院醫學系，並於臺大醫院完成內科住院醫師及新陳代謝暨內分泌科次專科訓練，其後於國立臺灣大學臨床醫學研究所取得碩士與博士學位。 李教授長期參與糖尿病相關學術研究與公共事務。2007年至2019年間曾擔任中華民國糖尿病學會副秘書長，2019年起擔任該學會理事，並協助推動多項學術與公共衛生相關倡議。李教授亦積極參與學術出版工作，目前擔任多本國際期刊編輯，包括亞洲糖尿病學會官方期刊 Journal of Diabetes Investigation 及 Diabetes & Metabolism Journal。此外亦為《內科學誌》編輯委員，並曾擔任糖尿病學會與內分泌學會官方期刊 Formosan Journal of Endocrinology and Metabolism 主編。自2021年起，李教授擔任糖尿病關懷基金會執行長，致力於提升社會大眾對糖尿病之認識並促進糖尿病照護品質。 李教授長期從事糖尿病與代謝疾病之流行病學與轉譯醫學研究，迄今已發表超過150篇SCI論文並參與20餘本專書撰寫，多篇研究成果刊登於國際重要期刊，包括 Diabetes Care、Diabetes、Journal of Clinical Endocrinology & Metabolism、American Journal of Obstetrics and Gynecology、Ultrasound in Obstetrics & Gynecology、International Journal of Obesity 及 FASEB Journal 等。其研究的一個重要主軸為孕期代謝異常，特別是妊娠糖尿病及其對母體與新生兒健康結果的影響。相關研究涵蓋妊娠糖尿病篩檢策略、孕期代謝變化、胎兒生長以及懷孕結局等議題。他主持完成之 TESGO 隨機對照試驗（randomized controlled trial）發表於 Diabetes Care，為少數由亞洲研究團隊主導、評估妊娠糖尿病篩檢策略之研究者發起隨機對照試驗之一。此外，他亦利用大型世代研究與全國性資料庫進行糖尿病與心血管代謝疾病之研究，探討相關疾病之風險因子、臨床預後與疾病負擔，並進一步結合臨床資料、生物標記研究與基礎研究，發展潛在的疾病預測與治療標的。他所進行一系列有關 vascular adhesion protein-1的轉譯研究，證實其為糖尿病併發症的生物標記，並且是心血管代謝疾病的潛在治療標的。 基於在研究領域的貢獻，李教授於2011年獲頒中華民國糖尿病學會暨中華民國內分泌學會「陳芳武教授傑出研究獎」，並於2023年獲頒亞洲糖尿病學會（Asian Association for the Study of Diabetes）「Masato Kasuga Award for Outstanding Scientific Achievement」。Professor Hung-Yuan Li is Professor of Internal Medicine at the College of Medicine, National Taiwan University, and an attending physician in the Division of Endocrinology and Metabolism at National Taiwan University Hospital. He is a leading researcher in the fields of diabetes epidemiology, cardiometabolic diseases, and metabolic disorders during pregnancy. He received his M.D. from National Taiwan University and completed his residency training in internal medicine and fellowship training in endocrinology and metabolism at National Taiwan University Hospital. He subsequently obtained both his Master’s and Ph.D. degrees from the Graduate Institute of Clinical Medicine at National Taiwan University. Professor Li has long been actively involved in academic and public health activities related to diabetes. From 2007 to 2019 he served as Deputy Secretary-General of the Diabetes Association of the Republic of China, and since 2019 he has served as a member of its Board of Directors. He currently serves as an editor of several international journals, including the Journal of Diabetes Investigation, and previously served as Editor-in-Chief of the Formosan Journal of Endocrinology and Metabolism. Since 2021, he has also been Chief Executive Officer of the Formosan Diabetes Care Foundation, promoting public awareness and improving diabetes care in Taiwan. Professor Li’s research focuses on the epidemiology and translational medicine of diabetes and metabolic diseases. He has published more than 150 SCI-indexed papers and contributed to over 20 book chapters, with work appearing in high-impact journals such as Diabetes Care, Diabetes, Journal of Clinical Endocrinology & Metabolism, American Journal of Obstetrics and Gynecology, Ultrasound in Obstetrics & Gynecology, International Journal of Obesity, and FASEB Journal. A major theme of his work is metabolic disorders during pregnancy, particularly gestational diabetes mellitus, and their impact on maternal and neonatal outcomes. He led the TESGO randomized controlled trial, published in Diabetes Care, which is one of the few investigator-initiated randomized controlled trials led by an Asian research team evaluating screening strategies for gestational diabetes. In addition, he has conducted extensive research on cardiometabolic diseases using large-scale cohort studies and nationwide databases, as well as translational and basic studies of several candidate genes. Importantly, a series of translational studies on vascular adhesion protein-1 (VAP-1) conducted by Professor Li has demonstrated its role as both a biomarker of diabetes complications and a potential therapeutic target in cardiometabolic diseases. In recognition of his research contributions, Professor Li received the Professor Fang-Wu Chen Outstanding Research Award from the Diabetes Association of the Republic of China and the Endocrine Society of the Republic of China in 2011, and the Masato Kasuga Award for Outstanding Scientific Achievement from the Asian Association for the Study of Diabetes in 2023.Epidemiology of DiabetesThe Application of Biomarkers糖尿病甲狀腺其他代謝內分泌疾病