Selective inhibition of HDAC6 promotes bladder cancer radiosensitization and mitigates the radiation-induced CXCL1 signalling

YU-CHIEH TSAIWang, Tzu-YinTzu-YinWangHsu, Chia-LangChia-LangHsuWEI-CHOU LINChen, Jyun-YuJyun-YuChenLi, Jia-HuaJia-HuaLiYEONG-SHIAU PUANN-LII CHENGCHIA-HSIEN CHENGSHENG-FANG SU2023-03-172023-03-172023-02-2100070920https://scholars.lib.ntu.edu.tw/handle/123456789/629356Although trimodality therapy resecting tumours followed by chemoradiotherapy is emerged for muscle-invasive bladder cancer (MIBC), chemotherapy produces toxicities. Histone deacetylase inhibitors have been identified as an effective strategy to enhance cancer radiotherapy (RT).enSelective inhibition of HDAC6 promotes bladder cancer radiosensitization and mitigates the radiation-induced CXCL1 signallingjournal article10.1038/s41416-023-02195-0368109122-s2.0-85148428324https://api.elsevier.com/content/abstract/scopus_id/85148428324