Chang, Xue-YongXue-YongChangWAN-YU LIN2023-09-112023-09-112023-06-0318687075https://scholars.lib.ntu.edu.tw/handle/123456789/635341Smoking can lead to the deterioration of lung function and susceptibility to diabetes. Recently, smoking was found to induce DNA methylation (DNAm) changes in some cytosine-phosphate-guanine sites (CpGs). As linear combinations of DNAm levels of aging-related CpGs, five measures of epigenetic age acceleration (EAA) have received extensive attention: HannumEAA, IEAA, PhenoEAA, GrimEAA, and DunedinPACE. It is of interest to explore whether some measures of EAA can mediate the associations of smoking with diabetes-related outcomes and indices of ventilatory lung function.enAging; Chronological age; DNA methylation; Epigenetic clock; Methylation clock[SDGs]SDG3journal article10.1186/s13148-023-01512-x372689822-s2.0-85160902477https://api.elsevier.com/content/abstract/scopus_id/85160902477