Mitochondria and cytochrome components released into the plasma of severe COVID-19 and ICU acute respiratory distress syndrome patients

Chen, Zhuo ZhenZhuo ZhenChenJohnson, LloydLloydJohnsonTrahtemberg, UrielUrielTrahtembergBaker, AndrewAndrewBakerHuq, SaaimatulSaaimatulHuqDufresne, JaimieJaimieDufresneBowden, PeterPeterBowdenMiao, MingMingMiaoJA-AN ANNIE HOCHENG-CHIH HSUDos Santos, Claudia CClaudia CDos SantosMarshall, John GJohn GMarshall2023-05-112023-05-112023-04-081542-6416https://scholars.lib.ntu.edu.tw/handle/123456789/630981Proteomic analysis of human plasma by LC-ESI-MS/MS has discovered a limited number of new cellular protein biomarkers that may be confirmed by independent biochemical methods. Analysis of COVID-19 plasma has indicated the re-purposing of known biomarkers that might be used as prognostic markers of COVID-19 infection. However, multiple molecular approaches have previously indicated that the SARS-COV2 infection cycle is linked to the biology of mitochondria and that the response to infections may involve the action of heme containing oxidative enzymes.enELECTROSPRAY-IONIZATION; LIQUID-CHROMATOGRAPHY; PROTEINS; TANDEM; LUCIGENIN; DNA; IDENTIFICATION; PEPTIDES; ENZYME[SDGs]SDG3Mitochondria and cytochrome components released into the plasma of severe COVID-19 and ICU acute respiratory distress syndrome patientsjournal article10.1186/s12014-023-09394-0370311812-s2.0-85153053738WOS:000967237700002https://api.elsevier.com/content/abstract/scopus_id/85153053738