HSIN-YUN SUNShields R.K.Cacciarelli T.V.Muder R.R.Singh N.2020-12-292020-12-2920101398-2273https://www.scopus.com/inward/record.uri?eid=2-s2.0-78650083100&doi=10.1111%2fj.1399-3062.2010.00543.x&partnerID=40&md5=4c20475fbc3a843d9e5507fddd33def6https://scholars.lib.ntu.edu.tw/handle/123456789/535431Both bacteremia and biliary cast syndrome are serious post-transplant complications in liver transplant recipients. In the setting of increasing drug resistance in the current era, management of infections caused by multidrug-resistant (MDR) bacteria has proven challenging. We present a case of a liver transplant recipient who developed biliary cast syndrome and intractable MDR Pseudomonas bacteremia that failed to resolve with conventional antimicrobial therapy and which was finally controlled by a novel combination regimen of colistimethate, doripenem, and tobramycin. Future studies validating the clinical efficacy of this combination strategy are warranted. ? 2010 John Wiley & Sons A/S.[SDGs]SDG3ciprofloxacin; colistimethate; doripenem; piperacillin plus tazobactam; prednisone; rifampicin; tacrolimus; tobramycin; adult; antibiotic sensitivity; article; bacteremia; biliary cast syndrome; biliary tract disease; biliary tract drainage; case report; chronic kidney disease; diabetes mellitus; drug withdrawal; follow up; graft recipient; hepatitis C; human; liver cell carcinoma; liver cirrhosis; liver graft; liver graft rejection; liver transplantation; male; multidrug resistance; nonhuman; priority journal; Pseudomonas aeruginosa; renal replacement therapy; retransplantation; Anti-Bacterial Agents; Bacteremia; Bile Duct Diseases; Carbapenems; Colistin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Liver Transplantation; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcomejournal article10.1111/j.1399-3062.2010.00543.x20626709