CHIA-TER CHAOCHIH-KANG CHIANG2021-08-202021-08-2020121011-7571https://www.scopus.com/inward/record.uri?eid=2-s2.0-84864968699&doi=10.1159%2f000339083&partnerID=40&md5=e684bb0037de99cb899838c4d61b7b2ahttps://scholars.lib.ntu.edu.tw/handle/123456789/578804Objective: To report a case of huge hepatocellular carcinoma associated with tumor lysis syndrome and its management. Clinical Presentation and Intervention: A 51-year-old hepatitis B carrier visited our clinic with progressive weight loss over recent months. Abdominal ultrasonography and magnetic resonance imaging revealed a huge hepatic mass in a cirrhotic liver, identified as hepatocellular carcinoma. A hepatologist and surgeon recommended transarterial chemoembolization followed by hepatectomy. The patient underwent the procedure, with the complication of tumor lysis syndrome. He was treated with a single high dose (9 mg) of rasburicase and his clinical condition improved dramatically, with acute kidney injury subsiding without emergent hemodialysis. Conclusions: This was a case of hepatocellular carcinoma with tumor lysis syndrome and acute kidney injury, treated successfully with rasburicase. Copyright ? 2012 S. Karger AG, Basel.[SDGs]SDG3rasburicase; abdominal pain; acute kidney failure; adult; article; case report; chemoembolization; drug megadose; echography; fever; hepatitis B; human; liver cell carcinoma; liver cirrhosis; liver resection; liver tumor; male; nuclear magnetic resonance imaging; oliguria; single drug dose; tumor lysis syndrome; urine volume; Carcinoma, Hepatocellular; Gout Suppressants; Humans; Liver Neoplasms; Male; Middle Aged; Tumor Lysis Syndrome; Urate Oxidasejournal article10.1159/000339083226878142-s2.0-84864968699