2006-08-012024-05-17https://scholars.lib.ntu.edu.tw/handle/123456789/680406摘要：土肉桂是臺灣固有的本土闊葉樹種之一，生長於本省中低海拔山區闊葉樹林中，因其「葉子」精油含有與大陸菌桂皮油相似的成分，十分值得重視而予以開發利用。目前所發表的相關文獻顯示，臺灣土肉桂二次代謝物的研究僅止於精油的成分分析與精油的生物活性評估，由本研究室初步試驗結果得知臺灣土肉桂葉子精油具有良好之抗真菌、抗&#34766;、抗病媒蚊幼蟲、抗白蟻與抗細菌活性，至於臺灣土肉桂葉子二次代謝物及其化合物的生物活性，則尚無相關的研究報告，因此，本計畫擬評估土肉桂葉子二次代謝物之抗氧化活性，及其生合成機制。本計畫如能順利完成，將可了解臺灣土肉桂葉子二次代謝物的抗氧化活性，並使具有抗氧化活性之成分應用於保健及醫療等用途，進而達到擴展森林產物利用領域及提高其經濟價值之目的。<br> Abstract: Cinnamomum osmophloeum Kaneh. is one of the indigenous hardwood species to Taiwan. Chemical constituents of its leaf essential oils are similar to those of famous Cinnamomum cassia bark oils, so the potential utilizations of C. osmophloeum are worthy of exploration. Results from our preliminary studies demonstrated that leaf essential oils from C. osmophloeum had excellent antifungal, antimite, antimosquito larve, antitermite and antibacterial activities. However, to the best of our knowledge there are very limited prior studies on the bioactivities of extractives from C. osmophloeum. Therefore, the objectives of this project are to evaluate the antioxidant activity of secondary metabolites from the leaf of C. osmophloeum, to identify the chemical structures of antioxidant compounds, and to understand the biosynthesis mechanisms of secondary metabolites. Through this study, it is expected that antioxidant compounds isolated from C. osmophloeum leaf extracts be of great potential as medicines for disease control or as raw materials for synthesizing useful analogues in industry.土肉桂葉子二次代謝物抗氧化活性細胞培養Cinnamomum osmophloeumLeafSecondary metaboliteAntioxidant activityCell culture