Hsieh M.-H.Chiou S.-C.Chen C.-C.Hsu W.-H.Jeng L.-B.YI-CHENG CHANGLin J.-D.2022-03-102022-03-1020100929-6441https://www.scopus.com/inward/record.uri?eid=2-s2.0-77950191476&doi=10.1016%2fS0929-6441%2810%2960004-5&partnerID=40&md5=2f786468364c64d56a4b5c0bc5cbf9f2https://scholars.lib.ntu.edu.tw/handle/123456789/597050The aim of the present study was to examine the anatomical differences in volumetric and intraparenchymal vascular parameters between the two thyroid lobes of patients with goiter, using three-dimensional power Doppler ultrasound. A total of 89 outpatients with goiter, including 55 with autoimmune thyroid disease (ATD) and 34 with simple goiter (SG), were evaluated by three-dimensional power Doppler ultrasound. Volumetric and intraparenchymal vascular indices including vascularization index, flow index and vascular flow index of each lobe were measured using the Virtual Organ Computer-Aided Analysis system. In all patients with goiter, the volume and vascular indices (vascularization index, flow index and vascular flow index) of the right thyroid lobe were significantly greater than those of the left lobe (p < 0.05). Differences in vascular indices were present in SG but not in ATD. ATD was associated with a larger thyroid volume and higher vascular indices compared with those of SG (p < 0.001), but there were no significant differences in volumetry and vascular indices between euthyroid ATD and SG. In conclusion, the right thyroid lobe was found to be significantly larger and more vascular than the left lobe in subjects with goiter, as measured by three-dimensional power Doppler ultrasound. In addition, ATD was associated with a higher thyroid volume and vascular indices compared with those of SG. ? 2010 Chinese Taipei Society of Ultrasound in Medicine & Elsevier.Three-dimensional ultrasound; Vascular index[SDGs]SDG3adolescent; adult; article; autoimmune thyroiditis; blood flow; child; Doppler echography; female; goiter; human; major clinical study; male; outpatient; school child; three dimensional imaging; thyroid gland; vascularization; volumetryjournal article10.1016/S0929-6441(10)60004-52-s2.0-77950191476