Duh, Chang-YihChang-YihDuhEl-Gamal, Ali Ali H.Ali Ali H.El-GamalChiang, Chin-YingChin-YingChiangChu, Chih-JuChih-JuChuWang, Shang-KweiShang-KweiWangCHANG-FENG DAI2009-12-172018-06-282009-12-172018-06-282002http://www.scopus.com/inward/record.url?eid=2-s2.0-0036931607&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/297324http://ntur.lib.ntu.edu.tw/bitstream/246246/174315/1/24.pdfSeven new cytotoxic xenicane-type diterpenoids, 9-deoxyxeniloide-E (1), 9-deoxy-7,8-epoxyxeniloide-E (2), xeniolide-G (3), 9-deoxyxenialactol-C (4), xenibecin (5), xeniolide-H (6), and xenitacin (7), were isolated from the methylene chloride solubles of the Formosan soft coral Xenia umbellata. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.application/pdf77646 bytesapplication/pdfen-US[SDGs]SDG39 deoxy 7,8 epoxyxeniloide E; 9 deoxyxenialactol C; 9 deoxyxeniloide E; dichloromethane; diterpenoid; unclassified drug; xenibecin; xeniolide G; xeniolide H; xenitacin; article; cancer cell culture; carbon nuclear magnetic resonance; controlled study; drug cytotoxicity; drug isolation; human; human cell; in vitro study; nuclear Overhauser effect; proton nuclear magnetic resonance; stereochemistry; structure activity relation; Animals; Anthozoa; Antineoplastic Agents; Chromatography, Thin Layer; Colonic Neoplasms; Diterpenes; Drug Screening Assays, Antitumor; Leukemia P388; Lung Neoplasms; Mice; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Taiwan; Tumor Cells, Cultured; Alcyonacea; Anthozoajournal article10.1021/np020268z2-s2.0-0036931607WOS:000180190100026http://ntur.lib.ntu.edu.tw/bitstream/246246/174315/1/24.pdf