Association between maternal benzodiazepine or Z-hypnotic use in early pregnancy and the risk of stillbirth, preterm birth, and small for gestational age: a nationwide, population-based cohort study in Taiwan

Meng, Lin-ChiehLin-ChiehMengLin, Chih-WanChih-WanLinLin, Yi-ChinYi-ChinLinHuang, Shih-TsungShih-TsungHuangChen, Yi-YungYi-YungChenCHI-YUNG SHANGCHIA-YI WUChen, Liang-KungLiang-KungChenKIN-WEI CHANFEI-YUAN HSIAO2023-08-012023-08-012023-0722150366https://scholars.lib.ntu.edu.tw/handle/123456789/634401Benzodiazepines and Z-hypnotics are commonly prescribed for anxiety and insomnia during pregnancy, but the evidence regarding potential adverse neonatal outcomes is insufficient because of poor control for confounding factors in previous studies. We therefore aimed to evaluate the association between the use of benzodiazepines or Z-hypnotics during early pregnancy and adverse neonatal outcomes (stillbirth, preterm birth, and small for gestational age).en[SDGs]SDG3Association between maternal benzodiazepine or Z-hypnotic use in early pregnancy and the risk of stillbirth, preterm birth, and small for gestational age: a nationwide, population-based cohort study in Taiwanjournal article10.1016/S2215-0366(23)00148-7373532622-s2.0-85162143680https://api.elsevier.com/content/abstract/scopus_id/85162143680